Update on the diagnosis and management of Wilson disease

EA Roberts - Current gastroenterology reports, 2018 - Springer
Abstract Purpose of Review Exciting developments relating to Wilson disease (WD) have
taken place with respect to both basic biological and clinical research. This review critically …

[HTML][HTML] Permissive regulation: A critical review of the regulatory history of buprenorphine formulations in Canada

A Sud, M McGee, B Mintzes, M Herder - International Journal of Drug …, 2022 - Elsevier
Suboxone (buprenorphine-naloxone) is an opioid product approved in the US and Canada
for the treatment of opioid use disorder. The drug is considered an important response to the …

[HTML][HTML] Cost-based price calculation of mexiletine for nondystrophic myotonia

S van den Berg, V van der Wel, SJ de Visser… - Value in Health, 2021 - Elsevier
Objectives Mexiletine is a long-known drug used for the treatment of arrhythmias and
repurposed in the 1980s for patients with nondystrophic myotonia (NDM). Recently, the price …

[HTML][HTML] Literature Review on Health Emigration in Rare Diseases—A Machine Learning Perspective

M Skweres-Kuchta, I Czerska, E Szaruga - International Journal of …, 2023 - mdpi.com
The article deals with one of the effects of health inequalities and gaps in access to
treatments for rare diseases, namely health-driven emigration. The purpose of the paper is …

[HTML][HTML] The Impact of Suboxone's Market Exclusivity on Cost of Opioid Use Disorder Treatment

M McGee, K Chiu, R Moineddin, A Sud - Applied health economics and …, 2023 - Springer
Background Buprenorphine-naloxone is an essential part of the response to opioid
poisoning rates in North America. Manipulating market exclusivity is a strategy …

High-cost drugs for rare diseases: their expenditure and value based on a regional area-based study

S Manea, L Visonà Dalla Pozza… - Health Services …, 2024 - journals.sagepub.com
Background: in the field of rare diseases (RDs) most of the European studies on budget
impact analysis of drugs that have been conducted often lay on theoretical assumptions and …

Does an orphan drug policy make a difference in access? A comparison of Canada and Australia

J Lexchin, N Moroz - International Journal of Health Services, 2020 - journals.sagepub.com
Canada has been discussing whether to implement an orphan drug policy for more than 25
years. Recently, the federal government announced funding for orphan drugs starting in …

Reforming Canada's Special Access Programme (SAP) to improve access to off-patent essential medicines

AR Houston, CM Blais, S Houston… - Official Journal of the …, 2018 - jammi.utpjournals.press
Many essential medicines, including basic drugs such as albendazole, do not have approval
to be marketed in Canada. Instead, they are only available through a federal government …

[PDF][PDF] Hubungan Tingkat Stres dengan Peningkatan Kadar Gula Darah Pada Pasien Diabetes Mellitus Tipe 2 di Poli Penyakit Dalam RSUD Kabupaten Bintan Tahun …

T Ina, RS Utami, S Natalia - Enhanc AJ Heal Sci, 2020 - scholar.archive.org
ABSTRAK Menurut data RSUD Kabupaten Bintan tahun 2017 DM tipe 2 menduduki urutan
tingkat pertama dalam sepuluh penyakit terbesar. Berdasarkan data pada tahun 2018 DM …

[PDF][PDF] Evidence and Policy in Pharmaceutical Regulation: The promise of, and barriers to, a system of adaptive licensing

K Fierlbeck, M Herder - International Conference on Public …, 2015 - ippapublicpolicy.org
In the regulation of pharmaceutical products, there is growing interest in moving to an
“adaptive licensing”(AL) model. Eichler et al.(2012) describe “adaptive licensing” as …