[HTML][HTML] Polypharmacy in older adults: a narrative review of definitions, epidemiology and consequences

F Pazan, M Wehling - European geriatric medicine, 2021 - Springer
Background The number of older adults has been constantly growing around the globe.
Consequently, multimorbidity and related polypharmacy have become an increasing …

An overview of prevalence, determinants and health outcomes of polypharmacy

M Khezrian, CJ McNeil, AD Murray… - … advances in drug …, 2020 - journals.sagepub.com
A high rate of polypharmacy is, in part, a consequence of the increasing proportion of
multimorbidity in the ageing population worldwide. Our understanding of the potential harm …

An update on the clinical consequences of polypharmacy in older adults: a narrative review

JW Wastesson, L Morin, ECK Tan… - Expert opinion on drug …, 2018 - Taylor & Francis
Introduction: Polypharmacy, the use of multiple medications by one individual, is
increasingly common among older adults. Caring for the growing number of older people …

[HTML][HTML] Polypharmacy, hospitalization, and mortality risk: a nationwide cohort study

TI Chang, H Park, DW Kim, EK Jeon, CM Rhee… - Scientific reports, 2020 - nature.com
Polypharmacy is a growing and major public health issue, particularly in the geriatric
population. This study aimed to examine the association between polypharmacy and the risk …

Association between polypharmacy and death: a systematic review and meta-analysis

N Leelakanok, AL Holcombe, BC Lund, X Gu… - Journal of the American …, 2017 - Elsevier
Objective Polypharmacy has been linked to a myriad of adverse consequences, and
escalating rates of polypharmacy present an emerging concern, particularly among older …

Polypharmacy and medication management in older adults

J Kim, AL Parish - Nursing Clinics, 2017 - nursing.theclinics.com
Although prescribed and over-the-counter medications may improve a wide range of health
problems, they also may cause or contribute to harm, especially in older adults. Current-day …

Associations between potentially inappropriate medications and adverse health outcomes in the elderly: a systematic review and meta-analysis

XX Xing, C Zhu, HY Liang, K Wang… - Annals of …, 2019 - journals.sagepub.com
Background: Adverse drug outcomes in the elderly have led to the development of lists of
potentially inappropriate medications (PIMs), such as the Beers criteria, and these PIMs …

Explicit criteria as clinical tools to minimize inappropriate medication use and its consequences

D Curtin, PF Gallagher… - Therapeutic advances in …, 2019 - journals.sagepub.com
Polypharmacy and prescribing of potentially inappropriate medications (PIMs) are the key
elements of inappropriate medication use (IMU) in older multimorbid people. IMU is …

[HTML][HTML] Quality of anticholinergic burden scales and their impact on clinical outcomes: a systematic review

A Lisibach, V Benelli, MG Ceppi… - European journal of …, 2021 - Springer
Purpose Older people are at risk of anticholinergic side effects due to changes affecting drug
elimination and higher sensitivity to drug's side effects. Anticholinergic burden scales (ABS) …

[HTML][HTML] A review of published anticholinergic scales and measures and their applicability in database analyses

G Lozano-Ortega, KM Johnston, A Cheung… - Archives of gerontology …, 2020 - Elsevier
Background/objectives: Available metrics for characterizing cumulative anticholinergic
exposure over time may not be well suited for use across all US data sources. In this review …