[HTML][HTML] Safety of the long-term use of proton pump inhibitors

ABR Thomson, MD Sauve, N Kassam… - World journal of …, 2010 - ncbi.nlm.nih.gov
The proton pump inhibitors (PPIs) as a class are remarkably safe and effective for persons
with peptic ulcer disorders. Serious adverse events are extremely rare for PPIs, with case …

[HTML][HTML] Proton-pump inhibitor use and fracture risk: an updated systematic review and meta-analysis

Y Nassar, S Richter - Journal of bone metabolism, 2018 - ncbi.nlm.nih.gov
Background This study's objective was to evaluate the association between proton-pump
inhibitor (PPI) use and bone fracture incidence and bone mineral density (BMD) by meta …

Use of acid-suppressive drugs and risk of fracture: a meta-analysis of observational studies

CS Eom, SM Park, SK Myung, JM Yun… - The Annals of Family …, 2011 - Annals Family Med
PURPOSE Previous studies have reported inconsistent findings regarding the association
between the use of acid-suppressive drugs such as proton pump inhibitors (PPIs) and …

Low-energy femoral fractures associated with the long-term use of bisphosphonates: a case series from a Swiss university hospital

K Ing-Lorenzini, J Desmeules, O Plachta, D Suva… - Drug Safety, 2009 - Springer
Background: Bisphosphonates are effective and well tolerated anti-resorptive drugs used for
the treatment of osteoporosis. However, some concerns about their potential long-term …

Effects of selective serotonin reuptake inhibitors on bone health in adults: time for recommendations about screening, prevention and management?

EM Haney, SJ Warden, MM Bliziotes - Bone, 2010 - Elsevier
Evidence regarding a functional serotonin (5-hydroxytryptamine) signaling system in bone
has generated considerable recent interest. The specific biochemical nature of …

Proton pump inhibitors therapy and risk of hip fracture: a systematic review and meta-analysis

X Ye, H Liu, C Wu, Y Qin, J Zang, Q Gao… - European journal of …, 2011 - journals.lww.com
Methods We systematically searched PubMed, EMBASE, and the Cochrane Library. We
included studies assessing the effects of PPIs on hip fracture. Data from the studies about …

[HTML][HTML] Acid-suppressive therapy and risk of infections: pros and cons

L Fisher, A Fisher - Clinical drug investigation, 2017 - Springer
This narrative review summarises the benefits, risks and appropriate use of acid-
suppressing drugs (ASDs), proton pump inhibitors and histamine-2 receptor antagonists …

Overcoming the exacerbating effects of ranitidine on NSAID-induced small intestinal toxicity with quercetin: Providing a complete GI solution

DP Singh, SP Borse, M Nivsarkar - Chemico-Biological Interactions, 2017 - Elsevier
There is a need to find/discover novel leads to treat complex and/or multi-factorial-
pathogenic disease (s) like Nonsteroidal anti-inflammatory drugs (NSAID)-induced …

Rabeprazole: a review of its use in the management of gastric acid-related diseases in adults

CM Baldwin, SJ Keam - Drugs, 2009 - Springer
Summary Abstract Rabeprazole (Aciphex®, Alfence®, Pariet®) is a proton pump inhibitor
(PPI) used for the treatment of adults with conditions requiring a reduction of gastric acid …

Co-administration of quercetin with pantoprazole sodium prevents NSAID-induced severe gastroenteropathic damage efficiently: Evidence from a preclinical study in …

DP Singh, SP Borse, M Nivsarkar - Experimental and Toxicologic Pathology, 2017 - Elsevier
Management of Nonsteroidal anti-inflammatory drug (NSAID)-induced gastroenteropathy
has emerged as a major medical and socioeconomic problem mainly because the highly …