Valproic acid-induced encephalopathy: A review of clinical features, risk factors, diagnosis, and treatment

J Wu, J Li, W Jing, X Tian, X Wang - Epilepsy & Behavior, 2021 - Elsevier
Valproic acid (VPA), or sodium valproate, is a commonly used medication for seizure
disorders, migraines, and mental illness. Although VPA is relatively safe, it still has several …

Valproate-induced hyperammonemic encephalopathy and normal liver functions: possible synergism with topiramate

SI Deutsch, JA Burket, RB Rosse - Clinical neuropharmacology, 2009 - journals.lww.com
A patient with valproate-induced hyperammonemic encephalopathy presented with altered
mental status and hyperammonemia in the context of normal liver functions. Fortunately …

Incidence, Presentation, and Risk Factors for Sodium Valproate–Associated Hyperammonemia in Neurosurgical Patients: A Prospective, Observational Study

PYM Woo, AWY Woo, SW Lam, NMW Ko, JWK Ho… - World neurosurgery, 2020 - Elsevier
Objective Sodium valproate (VPA) is a commonly prescribed antiepileptic drug (AED) in
daily neurosurgical practice. However, the incidence of VPA-associated hyperammonemia …

Carbamazepine-induced hyperammonemia

EN Adams, A Marks, MH Lizer - American Journal of Health …, 2009 - academic.oup.com
Purpose. A case of carbamazepine-induced hyperammonemia is presented. Summary. A 26-
year-old man with bipolar disorder, seizures, and mild mental retardation secondary to a …

[PDF][PDF] Recurrent stupor associated with chronic valproic acid therapy and hyperammonemia

M Stefan, S Bavli - Hospital Physician, 2009 - Citeseer
Results of initial laboratory investigations includ ing complete blood count, electrolyte panel,
glucose levels, serum creatinine, liver function test, coagula tion profile, albumin, and thyroid …

[PDF][PDF] Carbamazepine induced asterixis with hyperammonemia: a case report with review of literature

H Singh, GB Nanjundappa, SK Reddi… - Indian Journal of …, 2015 - journals.sagepub.com
Carbamazepine is a commonly prescribed antiepileptic mood stabilizer for the treatment of
acute manic and mixed episodes associated with bipolar I disorder and in neuropathic …

Valproate-induced hyperammonemic encephalopathy in a renal transplanted patient

C Melexopoulou, S Marinaki, M Darema, C Skalioti… - Renal …, 2014 - Taylor & Francis
Neurological complications after renal transplantation constitute an important cause of
morbidity and mortality. Their differential diagnosis is difficult and essential for subsequent …

Possible new clinical sign of hyperammonemia

HA Pupko - CMAJ, 2008 - Can Med Assoc
Saleh Alqahtani and colleagues have provided a welcome reminder that hyperammonemia
is a common side effect of valproate therapy. 1 However, I am not convinced that …

[HTML][HTML] Valproate-induced encephalopathy with predominant pancerebellar syndrome

R Verma, P Kori - Indian Journal of Pharmacology, 2012 - journals.lww.com
Valproate-induced hyperammonemic encephalopathy is a rare event clinically characterized
by impaired sensorium, vomiting, headache, seizures and focal neurological deficits. The …

Current awareness: Pharmacoepidemiology and drug safety

John Wiley & Sons, Ltd. - 2003 - Wiley Online Library
In order to keep subscribers up‐to‐date with the latest developments in their field, John
Wiley & Sons are providing a current awareness service in each issue of the journal. The …