The urothelium: life in a liquid environment

MG Dalghi, N Montalbetti, MD Carattino… - Physiological …, 2020 - journals.physiology.org
The urothelium, which lines the renal pelvis, ureters, urinary bladder, and proximal urethra,
forms a high-resistance but adaptable barrier that surveils its mechanochemical …

Toilet-based continuous health monitoring using urine

S Tasoglu - Nature Reviews Urology, 2022 - nature.com
Regular health monitoring can result in early detection of disease, accelerate the delivery of
medical care and, therefore, considerably improve patient outcomes for countless medical …

[PDF][PDF] Proteomic and metabolomic profiling of urine uncovers immune responses in patients with COVID-19

X Bi, W Liu, X Ding, S Liang, Y Zheng, X Zhu, S Quan… - Cell reports, 2022 - cell.com
The utility of the urinary proteome in infectious diseases remains unclear. Here, we analyzed
the proteome and metabolome of urine and serum samples from patients with COVID-19 …

Molecular signatures of obstructive sleep apnea in adults: a review and perspective

ES Arnardottir, M Mackiewicz, T Gislason, KL Teff… - Sleep, 2009 - academic.oup.com
The consequences of obstructive sleep apnea (OSA) are largely mediated by chronic
intermittent hypoxia and sleep fragmentation. The primary molecular domains affected are …

VEGF signalling inhibition-induced proteinuria: mechanisms, significance and management

H Izzedine, C Massard, JP Spano, F Goldwasser… - European Journal of …, 2010 - Elsevier
Proteinuria is a dose-related side-effect occurring after inhibition of vascular endothelial
growth factor (VEGF) signalling and may reflect severe glomerular damage. The inhibition of …

[HTML][HTML] Nanoparticles in the diagnosis and treatment of vascular aging and related diseases

H Xu, S Li, YS Liu - Signal Transduction and Targeted Therapy, 2022 - nature.com
Aging-induced alternations of vasculature structures, phenotypes, and functions are key in
the occurrence and development of vascular aging-related diseases. Multiple molecular and …

[HTML][HTML] Urine proteome profiling predicts lung cancer from control cases and other tumors

C Zhang, W Leng, C Sun, T Lu, Z Chen, X Men… - …, 2018 - thelancet.com
Abstract Development of noninvasive, reliable biomarkers for lung cancer diagnosis has
many clinical benefits knowing that most of lung cancer patients are diagnosed at the late …

[HTML][HTML] Urinary markers of tubular injury in early diabetic nephropathy

T Fiseha, Z Tamir - International journal of nephrology, 2016 - hindawi.com
Diabetic nephropathy (DN) is a common and serious complication of diabetes associated
with adverse outcomes of renal failure, cardiovascular disease, and premature mortality …

Diabetic nephropathy: traditional to proteomic markers

RN Moresco, MB Sangoi, JAM De Carvalho, E Tatsch… - Clinica chimica acta, 2013 - Elsevier
Diabetic nephropathy (DN) is one of the major microvascular complications of diabetes and
it is defined as a rise in the urinary albumin excretion (UAE) rate and abnormal renal …

[HTML][HTML] Urine proteome of COVID-19 patients

Y Li, Y Wang, H Liu, W Sun, B Ding, Y Zhao, P Chen… - Urine, 2020 - Elsevier
Abstract The atypical pneumonia (COVID-19) caused by SARS-CoV-2 is a serious threat to
global public health. However, early detection and effective prediction of patients with mild to …