Background The purpose was to: 1) perform a systematic review of studies examining the
relation between physical activity, fitness, and health in school-aged children and youth, and …

Background The purpose was to conduct systematic reviews of the relationship between
physical activity of healthy community-dwelling older (> 65 years) adults and outcomes of …

This update of evidence-based guidelines (GL) aims to translate current evidence and
expert opinion into recommendations for multidisciplinary teams responsible for the optimal …

This systematic review examines critically the scientific basis for Canada's Physical Activity
Guide for Healthy Active Living for adults. Particular reference is given to the dose-response …

Objective To summarise the long term efficacy of anti-obesity drugs in reducing weight and
improving health status. Design Updated meta-analysis of randomised trials. Data sources …

Background The prevalence of obesity has increased over the past 3 decades, with a
disproportionate growth in excessive weight categories (body mass index [BMI] 35.0–39.9 …

Obesity is associated with increased risk of developing metabolic syndrome (MetS), type 2
diabetes mellitus (T2DM) and cardiovascular disease (CVD) leading to higher all-cause …

BACKGROUND & AIMS: The appropriate alanine aminotransferase (ALT) threshold value to
use for diagnosis of chronic liver disease in children is unknown. We sought to develop …

Weight stigma is rooted in a fundamental misunderstanding of the origins of obesity, wherein
the interplay of behavioral, environmental, genetic, and metabolic factors is deemphasized …

Context: Recombinant human GH (rhGH) therapy in Prader-Willi syndrome (PWS) has been
used by the medical community and advocated by parental support groups since its …