Molecular principles of cancer invasion and metastasis
MF Leber, T Efferth - International journal of oncology, 2009 - spandidos-publications.com
The main threat and the reason for most cancer deaths are not the primary neoplasias, but
secondary tumors, the metastases. Drastic phenotypic and biochemical changes occur …
secondary tumors, the metastases. Drastic phenotypic and biochemical changes occur …
[HTML][HTML] Pluripotency transcription factors and cancer stem cells: small genes make a big difference
A Liu, X Yu, S Liu - Chinese journal of cancer, 2013 - ncbi.nlm.nih.gov
Cancer stem cells (CSCs) are thought to drive uncontrolled tumor growth, and the existence
of CSCs has recently been proven by direct experimental evidence, including tracing cell …
of CSCs has recently been proven by direct experimental evidence, including tracing cell …
The role of NANOG transcriptional factor in the development of malignant phenotype of cancer cells
N Gawlik-Rzemieniewska, I Bednarek - Cancer biology & therapy, 2016 - Taylor & Francis
abstract NANOG is a transcription factor that is involved in the self-renewal of embryonic
stem cells (ES) and is a critical factor for the maintenance of the undifferentiated state of …
stem cells (ES) and is a critical factor for the maintenance of the undifferentiated state of …
[HTML][HTML] Beyond bench and bedside: disentangling the concept of translational research
AL Van der Laan, M Boenink - Health care analysis, 2015 - Springer
Abstract The label 'Translational Research'(TR) has become ever more popular in the
biomedical domain in recent years. It is usually presented as an attempt to bridge a …
biomedical domain in recent years. It is usually presented as an attempt to bridge a …
[PDF][PDF] Silencing expression of the NANOG gene and changes in migration and metastasis of urinary bladder cancer cells
N Gawlik-Rzemieniewska, A Galilejczyk… - Archives of Medical …, 2016 - termedia.pl
Results: The qRTPCR evaluation showed that silencing the NANOG gene in T24 cells led to
the decrease of mRNA for the MMP-2I gene to the level of 62.4% and the MMP-9 gene to the …
the decrease of mRNA for the MMP-2I gene to the level of 62.4% and the MMP-9 gene to the …
Regulation of cancer stemness, cell signaling, reactive oxygen species, and microRNAs in cancer stem cells
G Chengizkhan, SK Thangavelu, S Muthusami… - Cancer Stem Cells and …, 2024 - Elsevier
MicroRNAs (miRNAs/miRs) are a class of endogenous short or small noncoding RNAs
(sncRNAs) that play an intrinsic role in the regulation of various cellular, physiological, and …
(sncRNAs) that play an intrinsic role in the regulation of various cellular, physiological, and …
[HTML][HTML] NANOG: a promising target for digestive malignant tumors
AX Sun, CJ Liu, ZQ Sun, Z Wei - World journal of gastroenterology …, 2014 - ncbi.nlm.nih.gov
NANOG has been extensively researched since its discovery by Chambers et al. NANOG is
a homeodomain transcription factor and an essential regulator of embryonic stem cell (ESC) …
a homeodomain transcription factor and an essential regulator of embryonic stem cell (ESC) …
[HTML][HTML] Translational research in oncology: Implications for palliative care
A Ghoshal - Indian journal of palliative care, 2017 - ncbi.nlm.nih.gov
The label “translational research”(TR) has become ever more popular in the biomedical
domain in recent years. It is usually presented as an attempt to bridge a supposed gap …
domain in recent years. It is usually presented as an attempt to bridge a supposed gap …
转换医学研究——让患者更快受益于医学科技
关健， 陈杰 - 基础医学与临床, 2008 - cqvip.com
随着生命科学的快速发展, 转换医学研究近年来受到越来越多的重视. 转换医学研究的目的是
打破基础医学与药物研发和临床医学之间的屏障, 缩短实验室到病床的过程 …
打破基础医学与药物研发和临床医学之间的屏障, 缩短实验室到病床的过程 …
Breast cancer stem cells and their niche: lethal seeds in lethal soil
D Balicki, B Leyland-Jones… - … of Breast Cancer, 2020 - taylorfrancis.com
In contrast, the cancer stem cell model suggests that only rare cancer stem cells have the
intrinsic ability to proliferate extensively to form new tumors. Stem cells are multipotent with …
intrinsic ability to proliferate extensively to form new tumors. Stem cells are multipotent with …