Cardiovascular risk and inhibition of cyclooxygenase: a systematic review of the observational studies of selective and nonselective inhibitors of cyclooxygenase 2
P McGettigan, D Henry - Jama, 2006 - jamanetwork.com
ContextEvidence that rofecoxib increases the risk of myocardial infarction has led to scrutiny
of other nonsteroidal anti-inflammatory drugs (NSAIDs). Regulatory agencies have provided …
of other nonsteroidal anti-inflammatory drugs (NSAIDs). Regulatory agencies have provided …
[HTML][HTML] Cardiovascular risk with non-steroidal anti-inflammatory drugs: systematic review of population-based controlled observational studies
P McGettigan, D Henry - PLoS medicine, 2011 - journals.plos.org
Background Randomised trials have highlighted the cardiovascular risks of non-steroidal
anti-inflammatory drugs (NSAIDs) in high doses and sometimes atypical settings. Here, we …
anti-inflammatory drugs (NSAIDs) in high doses and sometimes atypical settings. Here, we …
Problem of immortal time bias in cohort studies: example using statins for preventing progression of diabetes
Problem of immortal time bias in cohort studies: example using statins for preventing
progression of diabetes | The BMJ Skip to main content Intended for healthcare …
progression of diabetes | The BMJ Skip to main content Intended for healthcare …
COX2/mPGES1/PGE2 pathway regulates PD-L1 expression in tumor-associated macrophages and myeloid-derived suppressor cells
V Prima, LN Kaliberova, S Kaliberov… - Proceedings of the …, 2017 - National Acad Sciences
In recent years, it has been established that programmed cell death protein ligand 1 (PD-L1)–
mediated inhibition of activated PD-1+ T lymphocytes plays a major role in tumor escape …
mediated inhibition of activated PD-1+ T lymphocytes plays a major role in tumor escape …
Duration of treatment with nonsteroidal anti-inflammatory drugs and impact on risk of death and recurrent myocardial infarction in patients with prior myocardial …
AM Schjerning Olsen, EL Fosbøl, J Lindhardsen… - Circulation, 2011 - Am Heart Assoc
Background—Despite the fact that nonsteroidal anti-inflammatory drugs (NSAIDs) are
contraindicated among patients with established cardiovascular disease, many receive …
contraindicated among patients with established cardiovascular disease, many receive …
Adverse effects of analgesics commonly used by older adults with osteoarthritis: focus on non-opioid and opioid analgesics
BACKGROUND: Osteoarthritis (OA) is the most common cause of disability in older adults,
and although analgesic use can be helpful, it can also result in adverse drug events …
and although analgesic use can be helpful, it can also result in adverse drug events …
Increased mortality and cardiovascular morbidity associated with use of nonsteroidal anti-inflammatory drugs in chronic heart failure
GH Gislason, JN Rasmussen… - Archives of internal …, 2009 - jamanetwork.com
Background Accumulating evidence indicates increased cardiovascular risk associated with
nonsteroidal anti-inflammatory drug (NSAID) use, in particular in patients with established …
nonsteroidal anti-inflammatory drug (NSAID) use, in particular in patients with established …
Myocardial infarction and individual nonsteroidal anti‐inflammatory drugs meta‐analysis of observational studies
C Varas‐Lorenzo, N Riera‐Guardia… - … and drug safety, 2013 - Wiley Online Library
Objective To conduct a systematic review of observational studies on the risk of acute
myocardial infarction (AMI) with use of individual nonsteroidal anti‐inflammatory drugs …
myocardial infarction (AMI) with use of individual nonsteroidal anti‐inflammatory drugs …
Association of NSAID use with risk of bleeding and cardiovascular events in patients receiving antithrombotic therapy after myocardial infarction
AMS Olsen, GH Gislason, P McGettigan, E Fosbøl… - Jama, 2015 - jamanetwork.com
Importance Antithrombotic treatment is indicated for use in patients after myocardial
infarction (MI); however, concomitant use of nonsteroidal anti-inflammatory drugs (NSAIDs) …
infarction (MI); however, concomitant use of nonsteroidal anti-inflammatory drugs (NSAIDs) …
Drug–drug interactions between antithrombotic medications and the risk of gastrointestinal bleeding
Background: Anticoagulants and antiplatelet drugs (eg, warfarin, clopidogrel and
acetylsalicylic acid) are key therapeutic agents in the treatment of cardiovascular diseases …
acetylsalicylic acid) are key therapeutic agents in the treatment of cardiovascular diseases …