Short bowel syndrome and intestinal failure: consensus definitions and overview

SJD O'Keefe, AL Buchman, TM Fishbein… - Clinical …, 2006 - Elsevier
Short bowel syndrome (SBS)–associated intestinal failure is a highly disabling condition that
impairs quality of life and social integration. Although the condition is not uniformly fatal, it …

The therapeutic potential of manipulating gut microbiota in obesity and type 2 diabetes mellitus

RS Kootte, A Vrieze, F Holleman… - Diabetes, Obesity …, 2012 - Wiley Online Library
Obesity and type 2 diabetes mellitus (T2DM) are attributed to a combination of genetic
susceptibility and lifestyle factors. Their increasing prevalence necessitates further studies …

[PDF][PDF] Differentiation of human pluripotent stem cells into colonic organoids via transient activation of BMP signaling

JO Múnera, N Sundaram, SA Rankin, D Hill, C Watson… - Cell stem cell, 2017 - cell.com
Gastric and small intestinal organoids differentiated from human pluripotent stem cells
(hPSCs) have revolutionized the study of gastrointestinal development and disease. Distal …

[PDF][PDF] Intestinal brush border assembly driven by protocadherin-based intermicrovillar adhesion

SW Crawley, DA Shifrin, NE Grega-Larson… - Cell, 2014 - cell.com
Transporting epithelial cells build apical microvilli to increase membrane surface area and
enhance absorptive capacity. The intestinal brush border provides an elaborate example …

Micronutrient absorption and related outcomes in people with inflammatory bowel disease: a review

K Kilby, H Mathias, L Boisvenue, C Heisler, JL Jones - Nutrients, 2019 - mdpi.com
Inflammatory Bowel Disease (IBD) is a chronic disorder associated with immune
dysregulation and chronic inflammation of the digestive tract. While it is poorly understood …

Risk factors of non-alcoholic fatty liver disease in patients with inflammatory bowel disease

A Sourianarayanane, G Garg, TH Smith… - Journal of Crohn's …, 2013 - academic.oup.com
Background: Metabolic risk factors are associated with non-alcoholic fatty liver disease
(NAFLD), but they are less frequent in inflammatory bowel disease (IBD). Aim: This study …

[HTML][HTML] Patterning the gastrointestinal epithelium to confer regional-specific functions

CA Thompson, A DeLaForest, MA Battle - Developmental biology, 2018 - Elsevier
The gastrointestinal (GI) tract, in simplest terms, can be described as an epithelial-lined
muscular tube extending along the cephalocaudal axis from the oral cavity to the anus …

Enteric microbial flora, bacterial overgrowth, and short-bowel syndrome

JK DiBaise, RJ Young, JA Vanderhoof - Clinical Gastroenterology and …, 2006 - Elsevier
Small intestinal bacterial overgrowth (SIBO) occurs commonly in short-bowel syndrome
(SBS) and, in some instances, may result in significant problems. SIBO is characterized by a …

High prevalence of multiple micronutrient deficiencies in children with intestinal failure: a longitudinal study

CJ Yang, D Duro, D Zurakowski, M Lee, T Jaksic… - The Journal of …, 2011 - Elsevier
OBJECTIVE: To determine the prevalence of micronutrient deficiencies in children with
intestinal failure as they transitioned from parenteral nutrition (PN) to enteral nutrition (EN) …

Nutrition and fluid optimization for patients with short bowel syndrome

LE Matarese - Journal of Parenteral and Enteral Nutrition, 2013 - Wiley Online Library
Short bowel syndrome (SBS) is characterized by nutrient malabsorption and occurs
following surgical resection, congenital defect, or disease of the bowel. The severity of SBS …