Stolberg et al. have an effect on their health status. Such clinical maneuvers include
prevention strategies, screening programs, diagnostic tests, interventional procedures, the …

Background Many dentists or hygienists provide scaling and polishing for patients at regular
intervals, even for those at low risk of developing periodontal disease. There is debate over …

Randomised controlled trials are considered to be the best method to assess comparative
clinical efficacy and effectiveness, and can be a key source of data for estimating cost …

Rationale: Although commonly used as the primary outcome measure of clinical trials in
pulmonary arterial hypertension (PAH), the minimal important difference (MID) of the 6 …

Objective: Very preterm birth (< 30 weeks' gestation) is a stressful event for parents, and few
support interventions for these parents have been evaluated. In this study, we evaluated the …

Background Spin represents specific reporting strategies, either intentional or unintentional,
to convince the reader that the beneficial effect of the experimental intervention in terms of …

Formal statistical methods for analyzing clinical trial data are widely accepted by the medical
community. Unfortunately, the interpretation and reporting of trial results from the perspective …

OBJECTIVE: Randomized trials generally use “frequentist” statistics based on P-values and
95% confidence intervals. Frequentist methods have limitations that might be overcome, in …

Background There is a continuing debate on whether transcatheter arterial
chemoembolization (TACE) plus radiofrequency ablation (RFA) is more effective than RFA …

Background Mass media through the Internet is a powerful means of disseminating medical
research. We aimed to determine whether and how the interpretation of research results is …