Recommendations for the establishment of stroke systems of care: recommendations from the American Stroke Association's Task Force on the Development of Stroke …

Task Force Members, LH Schwamm, A Pancioli… - Stroke, 2005 - Am Heart Assoc
1994 and December 2003 to identify studies relevant to the treatment of stroke and the
establishment of stroke systems. A range of search terms* identified 1000 articles of …

Bench to bedside: the quest for quality in experimental stroke research

U Dirnagl - Journal of Cerebral Blood Flow & Metabolism, 2006 - journals.sagepub.com
Over the past decades, great progress has been made in clinical as well as experimental
stroke research. Disappointingly, however, hundreds of clinical trials testing neuroprotective …

Why are stroke patients excluded from TPA therapy? An analysis of patient eligibility

PA Barber, J Zhang, AM Demchuk, MD Hill… - Neurology, 2001 - AAN Enterprises
Background: Thrombolytic therapy for acute stroke (< 3 hours) will not have a major impact
on death and dependency unless it is accessible to more patients. Objective: To determine …

Fast assessment of stroke and transient ischaemic attack to prevent early recurrence (FASTER): a randomised controlled pilot trial

J Kennedy, MD Hill, KJ Ryckborst, M Eliasziw… - The Lancet …, 2007 - thelancet.com
Background Patients with transient ischaemic attack (TIA) or minor stroke are at high
immediate risk of stroke. The optimum early treatment options for these patients are not …

Revised and updated recommendations for the establishment of primary stroke centers: a summary statement from the brain attack coalition

MJ Alberts, RE Latchaw, A Jagoda, LR Wechsler… - Stroke, 2011 - Am Heart Assoc
Background and Purpose—The formation and certification of Primary Stroke Centers has
progressed rapidly since the Brain Attack Coalition's original recommendations in 2000. The …

The neurotoxicity of tissue plasminogen activator?

J Kaur, Z Zhao, GM Klein, EH Lo… - Journal of Cerebral …, 2004 - journals.sagepub.com
Tissue plasminogen activator (tPA), a fibrin specific activator for the conversion of
plasminogen to plasmin, stimulates thrombolysis and rescues ischemic brain by restoring …

Hemi-orolingual angioedema and ACE inhibition after alteplase treatment of stroke

MD Hill, T Lye, H Moss, PA Barber, AM Demchuk… - Neurology, 2003 - AAN Enterprises
One hundred seventy-six consecutive patients treated with IV tissue plasminogen activator
(tPA) for acute ischemic stroke were examined prospectively, and orolingual angioedema …

Intravenous tissue-type plasminogen activator therapy for ischemic stroke: Houston experience 1996 to 2000

JC Grotta, WS Burgin, A El-Mitwalli, M Long… - Archives of …, 2001 - jamanetwork.com
Context Intravenous tissue-type plasminogen activator (tPA) therapy using the National
Institute of Neurological Disorders and Stroke criteria has been given with variable safety to …

Frequency of thrombolytic therapy in patients with acute ischemic stroke and the risk of in-hospital mortality: the German Stroke Registers Study Group

PU Heuschmann, K Berger, B Misselwitz, P Hermanek… - Stroke, 2003 - Am Heart Assoc
Background and Purpose—There is little information about early outcome after intravenous
application of tissue-type plasminogen activator (tPA) for stroke patients treated in …

Dual or mono antiplatelet therapy for patients with acute ischemic stroke or transient ischemic attack: systematic review and meta-analysis of randomized controlled …

CM Geeganage, HC Diener, A Algra, C Chen, EJ Topol… - Stroke, 2012 - Am Heart Assoc
Background and Purpose—Antiplatelets are recommended for patients with acute
noncardioembolic stroke or transient ischemic attack. We compared the safety and efficacy …