Folate administration substantially reduces the risk on neural tube defects (NTD). The
interest for studying a disturbed homocysteine (Hcy) metabolism in relation to NTD was …

The primary biological role of human skin pigmentation is as a mediator of penetration of
ultraviolet radiation (UVR) into the deep layers of skin and the cutaneous circulation. Since …

Neural tube defects are common and important congenital malformations. Over the past
decade a series of studies have demonstrated that there appears to be a reduction in both …

Neural tube defects were induced dose-dependently by single injections of the
anticonvulsant drug valproic acid (VPA) as sodium salt in mice on gestational day 8. Folinic …

Although theplethora'of pregnancy was recognized early in the 19th century and German
work as far back as 1854 showed a rise of blood volume in pregnant laboratory animals, the …

My interest in the subject of this book stemmed from my graduate studies at Columbia
University's Sergievsky Center between 1977 and 1980. It was there under the tutelage of …

Abstract Rat embryos (9.5‐day‐old) were cultured for 48 hours in serum from diet‐induced
folic‐acid‐deficient rats. Resultant embryos were frequently abnormal; many were growth …

The evidence for an association between vitamin deficiency in early pregnancy and the
prevalence of neural-tube defects in humans is reviewed, with particular emphasis on the …

Neural tube defects (NTDs) remain among the most common types of congenital anomalies,
although prevalence rates at birth of these defects have been declining in certain areas of …

The effect of the physiological and metabolic adjustments of pregnancy on nutrient utilization
in women is summarized. Emphasis is placed on those nutrients which have been reported …