Randomized, double-blind, cross-over trial comparing safety and efficacy of oral controlled-release oxycodone with controlled-release morphine in patients with …

…, R Fainsinger, A Darke, Z Harsanyi… - Journal of Clinical …, 1998 - ascopubs.org
PURPOSE Use of oxycodone for chronic cancer pain has been hampered by its short
elimination half-life. This study was designed to compare the efficacy and safety of controlled-…

Buprenorphine transdermal system in adults with chronic low back pain: a randomized, double-blind, placebo-controlled crossover study, followed by an open-label …

…, A Boulanger, PS Piraino, J Eisenhoffer, Z Harsanyi… - Clinical …, 2010 - Elsevier
Background: Buprenorphine is a mixed-activity, partial μ-opioid agonist. Its lipid solubility
makes it well suited for transdermal administration. Objective: This study assessed the efficacy …

Double blind randomized placebo control trial of controlled release codeine in the treatment of osteoarthritis of the hip or knee.

…, W Bensen, GT Thomson, Z Harsanyi… - The Journal of …, 2000 - europepmc.org
Objective Pain is the cardinal feature of osteoarthritis (OA), and with advancing disease
there is loss of function and increasing pain even at times of joint rest. Few studies have …

[HTML][HTML] Efficacy and safety of controlled-release oxycodone and standard therapies for postoperative pain after knee or hip replacement

…, PC Miceli, JL Reiz, Z Harsanyi… - Canadian journal of …, 2005 - ncbi.nlm.nih.gov
… Competing interests: Authors AC Darke, GAE Donnelly, LW Payne, JL Reiz and Z. Harsanyi
are full-time employees of Purdue Pharma and PC Micelli is a past employee and is a paid …

[HTML][HTML] A double-blind, crossover study of controlled-release metoclopramide and placebo for the chronic nausea and dyspepsia of advanced cancer

E Bruera, M Belzile, C Neumann, Z Harsanyi… - Journal of pain and …, 2000 - Elsevier
To compare a novel controlled-release formulation of metoclopramide with placebo in patients
with cancer-associated dyspepsia syndrome, 26 adult patients with a ⩾1 month history of …

Once-daily, controlled-release tramadol and sustained-release diclofenac relieve chronic pain due to osteoarthritis: a randomized controlled trial

…, J Wade, P Quigley, J Eisenhoffer, Z Harsanyi… - Pain Research and …, 2008 - hindawi.com
OBJECTIVE: The present study was a randomized, parallel, double-blind comparison between
controlled-release (CR) tramadol and sustained-release (SR) diclofenac in patients with …

Efficacy of controlled-release codeine in chronic non-malignant pain: a randomized, placebo-controlled clinical trial

…, A Sandler, B Goughnour, N Babul, Z Harsanyi… - Pain, 1995 - Elsevier
Treatment decisions for the use of opioid analgesics in chronic non-malignant pain are based
primarily on survey data, as evidence from well-controlled clinical trials has been lacking. …

Buprenorphine transdermal system for opioid therapy in patients with chronic low back pain

…, PS Piraino, P Quigley, Z Harsanyi… - Pain Research and …, 2010 - hindawi.com
OBJECTIVE: The present randomized, double-blinded, crossover study compared the
efficacy and safety of a seven-day buprenorphine transdermal system (BTDS) and placebo in …

Efficacy of Uniphyl, salbutamol, and their combination in asthmatic patients on high-dose inhaled steroids.

…, DI Small, M Alexander, A Day, Z Harsanyi… - American journal of …, 1995 - atsjournals.org
A group of 32 patients with moderately severe, chronic asthma (mean FEV1 55% of
predicted), maintained on moderately high doses of inhaled corticosteroids (mean dose 1,100 …

Controlled-release oxycodone and naloxone in the treatment of chronic low back pain: a placebo-controlled, randomized study

…, J Eisenhoffer, PS Piraino, Z Harsanyi… - Pain Research and …, 2013 - hindawi.com
BACKGROUND: For Canadian regulatory purposes, an analgesic study was required to
complement previously completed, pivotal studies on bowel effects and analgesia associated …