Omalizumab for aspirin hypersensitivity and leukotriene overproduction in aspirin-exacerbated respiratory disease. A randomized controlled trial

…, Y Kamide, Y Nakamura, Y Hamada… - American journal of …, 2020 - atsjournals.org
Rationale: Aspirin-exacerbated respiratory disease is characterized by severe asthma,
nonsteroidal antiinflammatory drug hypersensitivity, nasal polyposis, and leukotriene …

Frailty and muscle weakness in elderly patients with asthma and their association with cumulative lifetime oral corticosteroid exposure

…, K Yano, Y Nakamura, Y Hamada… - Allergology …, 2023 - jstage.jst.go.jp
Background: Frailty is a geriatric syndrome of age-related physiological decline, which is
associated with higher mortality and decreased healthy life expectancy, and muscle weakness …

Low-dose mepolizumab is effective as an add-on therapy for treating long-lasting peripheral neuropathy in patients with eosinophilic granulomatosis with polyangiitis

…, M Iwata, K Iwamoto, K Yano, Y Hamada… - Modern …, 2022 - academic.oup.com
Objective To assess the effectiveness of low-dose mepolizumab as an add-on therapy for
treating peripheral neurological symptoms in eosinophilic granulomatosis with polyangiitis (…

Computed tomography findings of paranasal sinuses in patients with eosinophilic granulomatosis with polyangiitis: comparison with other eosinophilic sinus diseases …

M Iwata, Y Fukutomi, Y Hamada, Y Nakamura… - Allergology …, 2023 - jstage.jst.go.jp
Background: Although paranasal sinuses are one of the most representative organs affected
by eosinophilic granulomatosis with polyangiitis (EGPA), they have not been studied …

[PDF][PDF] Genome-wide association study reveals an association between the HLA-DPB1∗ 02: 01: 02 allele and wheat-dependent exercise-induced anaphylaxis

K Fukunaga, Y Chinuki, Y Hamada, Y Fukutomi… - The American Journal of …, 2021 - cell.com
Wheat-dependent exercise-induced anaphylaxis (WDEIA) is a life-threatening food allergy
triggered by wheat in combination with the second factor such as exercise. The identification …

New sensitization to Aspergillus fumigatus in adult asthma over a 10-year observation period

…, K Nagayama, Y Nakamura, J Tanaka, Y Hamada… - 2018 - Eur Respiratory Soc
Background: Although the exposure and sensitization to respiratory (especially fungal)
allergens, represent key factors characterizing the presentation of asthma, studies regarding the …

Prevalence of inhaled allergen-specific IgE antibody positivity in the healthy Japanese population

…, Y Shiraishi, A Kitahara, T Oguma, Y Hamada… - Allergology …, 2022 - jstage.jst.go.jp
Background: Measurement of allergen-specific IgE antibodies to inhaled allergens is important
for the diagnosis and risk evaluation of allergic diseases such as asthma and allergic …

Treatable Traits in Asthma: The importance of extra-pulmonary traits-GERD, CRSwNP, Atopic Dermatitis, and Depression/Anxiety

VM McDonald, Y Hamada, A Agusti… - The Journal of Allergy and …, 2024 - Elsevier
Treatable traits is a personalised medicine approach to the management of airway disease.
Assessing traits within the three domains of pulmonary, extra pulmonary and behavioral/…

Optimal Aspergillus fumigatus and Asp f 1 serum IgG cut-offs for the diagnosis of allergic bronchopulmonary aspergillosis

Y Hamada, Y Fukutomi, E Nakatani, A Saito… - Allergology …, 2021 - jstage.jst.go.jp
Background: The presence of IgG antibodies (Abs) to Aspergillus fumigatus (Af) is a crucial
diagnostic criterion for allergic bronchopulmonary aspergillosis (ABPA). Although …

[HTML][HTML] Metagenomic gut microbiome analysis of Japanese patients with multiple chemical sensitivity/idiopathic environmental intolerance

…, M Iwata, K Nagayama, Y Nakamura, Y Hamada… - BMC microbiology, 2024 - Springer
Background Although the pathology of multiple chemical sensitivity (MCS) is unknown, the
central nervous system is reportedly involved. The gut microbiota is important in modifying …