Understanding complex biological systems requires extensive support from software tools.
Such tools are needed at each step of a systems biology computational workflow, which …

AIM: Although favourable outcomes in patients receiving extracorporeal cardiopulmonary
resuscitation (ECPR) for out-of-hospital cardiac arrest have been frequently reported in …

Background Work‐related psychosocial factors have been associated with metabolic
syndrome. However, no systematic reviews or meta‐analyses have evaluated this association. …

Gout based on hyperuricemia is a common disease with a genetic predisposition, which
causes acute arthritis. The ABCG2/BCRP gene, located in a gout-susceptibility locus on …

BACKGROUND: IgE-mediated peanut allergy is a complex trait with strong heritability, but its
genetic basis is currently unknown. Loss-of-function mutations within the filaggrin gene are …

… Contributors – T Sakamoto, K Nagao, Y Asai and N Morimura were the principal investigators,
and contributed to formulating the study concept, study design and completion, data …

The lung collectin surfactant protein A (SP-A) has been implicated in the regulation of
pulmonary host defense and inflammation. Zymosan induces proinflammatory cytokines in …

Inner ear hair cells convert the mechanical stimuli of sound, gravity, and head movement
into electrical signals. This mechanotransduction process is initiated by opening of cation …

Sensory transduction in auditory and vestibular hair cells requires expression of transmembrane
channel-like (Tmc) 1 and 2 genes, but the function of these genes is unknown. To …

Unidirectional fluid flow plays an essential role in the breaking of left-right (LR) symmetry in
mouse embryos, but it has remained unclear how the flow is sensed by the embryo. We …