Dendritic silica micro‐/nanoparticles with center‐radial pore structures, a kind of newly created
porous material, have attracted considerable attention owing to their unique open three‐…

Here we have identified 'triple D' (3d), a recessive N-ethyl-N-nitrosourea-induced mutation
and phenotype in which no signaling occurs via the intracellular Toll-like receptors 3, 7 and 9 (…

Graphitic carbon nitride (gC 3 N 4 ) has attracted enormous research attention as a promising
low cost, visible-light driven semiconductor photocatalyst. However, low photoabsorption …

Classical genetic methods, driven by phenotype rather than hypotheses, generally permit
the identification of all proteins that serve nonredundant functions in a defined biological …

Mesenchymal stromal cells (MSCs), also known as mesenchymal stem cells, have been
intensely investigated for clinical applications within the last decades. However, the majority of …

Mutations of the gene Lps selectively impede lipopolysaccharide (LPS) signal transduction
in C3H/HeJ and C57BL/10ScCr mice, rendering them resistant to endotoxin yet highly …

Several subsets of dendritic cells have been shown to produce type I IFN in response to viral
infections, thereby assisting the natural killer cell-dependent response that eliminates the …

Toll-like receptor 2 (TLR2) is required for the recognition of numerous molecular components
of bacteria 1 , 2 , 3 , 4 , 5 , 6 , 7 , 8 , fungi 9 , 10 and protozoa 11 . The breadth of the ligand …

Herpes simplex virus-1 (HSV-1) encephalitis (HSE) is the most common form of sporadic viral
encephalitis in western countries. Its pathogenesis remains unclear, as it affects otherwise …

The recessive mutation 'Heedless' (hdl) was detected in third-generation N-ethyl-N-nitrosourea–mutated
mice that showed defective responses to microbial inducers. Macrophages from …