Introduction Multiple structural brain changes in Alzheimer’s disease (AD) and mild cognitive
impairment (MCI) have been revealed on magnetic resonance imaging (MRI). There is a …

Background: There is no single generally accepted clinical definition of frailty. Previously
developed tools to assess frailty that have been shown to be predictive of death or need for …

… Ruobing Bai and Xiaowei Song are equally contributed to this work. … For example, Yu, Song
and co-workers hydrothermally synthesized Mg, Co-substituted aluminophosphate zeolites …

Extensive pre-mRNA back-splicing generates numerous circular RNAs (circRNAs) in human
transcriptome. However, the biological functions of these circRNAs remain largely unclear. …

The importance of the gut microbiome in central nervous system (CNS) diseases has long
been recognized; however, research into this connection is limited, in part, owing to a lack of …

… Author Contributions: Xiaowei Song conducted the analyses and co-wrote the first draft.
Arnold Mitnitski reviewed the analyses and obtained funding. Kenneth Rockwood conceived of …

Objectives: To construct and validate a frailty index (FI) that is clinically sensible and practical
for geriatricians by basing it on a routinely used comprehensive geriatric assessment (CGA…

Objectives: To investigate the relationship between accumulated health‐related problems (deficits),
which define a frailty index in older adults, and mortality in population‐based and …

Background The prevalence of frailty increases with age in older adults, but frailty is largely
unreported for younger adults, where its associated risk is less clear. Furthermore, less is …

OBJECTIVES: To measure relative fitness and frailty in older people without specific frailty
instruments and to relate that measurement to long‐term health outcomes. DESIGN: …