Diabetes and its comorbidities—where East meets West
Fetal programming associated with in utero exposure to maternal stress is thought to alter
gene expression, resulting in phenotypes that promote survival in a pathogen-rich and nutrient-…
gene expression, resulting in phenotypes that promote survival in a pathogen-rich and nutrient-…
Testosterone level in men with type 2 diabetes mellitus and related metabolic effects: A review of current evidence
KKT Cheung, AOY Luk, WY So… - Journal of diabetes …, 2015 - Wiley Online Library
A significant proportion of patients with type 2 diabetes mellitus have a low testosterone level
relative to reference ranges based on healthy young men. Only a small number of these …
relative to reference ranges based on healthy young men. Only a small number of these …
Aspects of multicomponent integrated care promote sustained improvement in surrogate clinical outcomes: a systematic review and meta-analysis
OBJECTIVE The implementation of the Chronic Care Model (CCM) improves health care
quality. We examined the sustained effectiveness of multicomponent integrated care in type 2 …
quality. We examined the sustained effectiveness of multicomponent integrated care in type 2 …
A variant in CDKAL1 influences insulin response and risk of type 2 diabetes
…, G Chen, H Huang, K Lashley, A Doumatey, WY So… - Nature …, 2007 - nature.com
We conducted a genome-wide association study for type 2 diabetes (T2D) in Icelandic cases
and controls, and we found that a previously described variant in the transcription factor 7-…
and controls, and we found that a previously described variant in the transcription factor 7-…
Two variants on chromosome 17 confer prostate cancer risk, and the one in TCF2 protects against type 2 diabetes
We performed a genome-wide association scan to search for sequence variants conferring
risk of prostate cancer using 1,501 Icelandic men with prostate cancer and 11,290 controls. …
risk of prostate cancer using 1,501 Icelandic men with prostate cancer and 11,290 controls. …
Metabolic profiles and treatment gaps in young-onset type 2 diabetes in Asia (the JADE programme): a cross-sectional study of a prospective cohort
…, LM Chuang, G Tutino, PC Tong, WY So… - The lancet Diabetes & …, 2014 - thelancet.com
Background The prevalence of diabetes is increasing in young adults in Asia, but little is known
about metabolic control or the burden of associated complications in this population. We …
about metabolic control or the burden of associated complications in this population. We …
Glomerular filtration rate, cardiorenal end points, and all-cause mortality in type 2 diabetic patients
OBJECTIVE—Chronic kidney disease (CKD) predicts cardiovascular disease (CVD) in the
general population. We investigated the effects of stages of renal function using the estimated …
general population. We investigated the effects of stages of renal function using the estimated …
[HTML][HTML] Whole-genome bisulfite sequencing of multiple individuals reveals complementary roles of promoter and gene body methylation in transcriptional regulation
Background DNA methylation is an important type of epigenetic modification involved in
gene regulation. Although strong DNA methylation at promoters is widely recognized to be …
gene regulation. Although strong DNA methylation at promoters is widely recognized to be …
Metabolic syndrome predicts new onset of chronic kidney disease in 5,829 patients with type 2 diabetes: a 5-year prospective analysis of the Hong Kong Diabetes …
OBJECTIVE—Type 2 diabetes is the leading cause of end-stage renal disease worldwide.
Aside from hyperglycemia and hypertension, other metabolic factors may determine renal …
Aside from hyperglycemia and hypertension, other metabolic factors may determine renal …
Risk association of HbA1c variability with chronic kidney disease and cardiovascular disease in type 2 diabetes: prospective analysis of the Hong Kong Diabetes …
… , and Dr Wing-Yee So and Prof Juliana Chan contributed to the final revision of the manuscript.
Dr Wing-Yee So is the guarantor and takes responsibility for the contents of this article. …
Dr Wing-Yee So is the guarantor and takes responsibility for the contents of this article. …