BACKGROUND: Airway remodeling is a key feature of persistent asthma and includes
alterations in the extracellular matrix protein profile around the airway smooth muscle (ASM) and …

Context Suicide bereavement remains understudied and poorly understood. Objectives To
examine outcomes of parents bereaved by the suicide death of their offspring and to compare …

Background Reducing treatment burden is a priority for people with cystic fibrosis, whose
health has benefited from using new modulators that substantially increase CFTR protein …

This report was prepared at the request of Manitoba Health, Healthy Living and Seniors (MHHLS)
as part of the contract between the University of Manitoba and MHHLS. It was …

Background Congenital anomalies of the kidney and urinary tract (CAKUT) are the primary
cause of chronic kidney disease in children. The relevance of timing of diabetes mellitus (DM) …

Background: Few population studies have examined the psychiatric outcomes of children
and adolescents in the child welfare system, and no studies have compared outcomes before …

BRCA1 is inactivated by gene mutations in >50% of familial breast and ovarian cancers.
BRCA1 is primarily a nuclear protein, although others previously reported cytoplasmic staining …

The objective of this study was to examine mental disorders and treatment use among
bereaved siblings in the general population. Siblings (N=7243) of all deceased children in the …

There is strong evidence to implicate transforming growth factor-β in the remodeling that
occurs in asthma, as levels are increased in bronchial lavage fluid and gene expression is …

We have previously shown that during pregnancy the E-twenty-six (ETS) transcription factor
ELF5 directs the differentiation of mammary progenitor cells toward the estrogen receptor (…