Polymorphism of the N-acetyltransferase 2 gene as a susceptibility risk factor for antituberculosis drug–induced hepatitis

YS Huang, HD Chern, WJ Su, JC Wu, SL Lai, SY Yang… - Hepatology, 2002 - Elsevier
Antituberculosis drug–induced hepatitis is one of the most prevalent drug-induced liver
injuries. Isoniazid is the major drug incriminated in this hepatotoxicity. Isoniazid is mainly …

[PDF][PDF] Cytochrome P450 2E1 genotype and the susceptibility to antituberculosis drug‐induced hepatitis

YS Huang, HD Chern, WJ Su, JC Wu, SC Chang… - …, 2003 - Wiley Online Library
Most cases with antituberculosis drug‐induced hepatitis have been attributed to isoniazid.
Isoniazid is metabolized by hepatic N‐acetyltransferase (NAT) and cytochrome P450 2E1 (…

Genetic polymorphisms of manganese superoxide dismutase, NAD (P) H: quinone oxidoreductase, glutathione S-transferase M1 and T1, and the susceptibility to drug …

YS Huang, WJ Su, YH Huang, CY Chen, FY Chang… - Journal of …, 2007 - Elsevier
BACKGROUND/AIMS: Drug metabolizing enzymes may be related to drug-induced liver
injury (DILI). Manganese superoxide dismutase (MnSOD), NAD(P)H:quinone oxidoreductase (…

Sleep apnea and risk of pneumonia: a nationwide population-based study

VYF Su, CJ Liu, HK Wang, LA Wu, SC Chang… - Cmaj, 2014 - Can Med Assoc
Background: Evidence evaluating the risk of pneumonia in patients with obstructive sleep
apnea is limited and mostly focuses on patients who receive continuous positive airway …

Statin use is associated with a lower risk of TB

VYF Su, WJ Su, YF Yen, SW Pan, PH Chuang, JY Feng… - Chest, 2017 - Elsevier
Background Statins are widely used to lower cholesterol levels and cardiovascular risk.
Further, studies have shown that statins may decrease the risks of infectious diseases and …

[HTML][HTML] Masks and medical care: two keys to Taiwan's success in preventing COVID-19 spread

VYF Su, YF Yen, KY Yang, WJ Su… - Travel Medicine and …, 2020 - ncbi.nlm.nih.gov
Despite being close to China, Taiwan has stopped the COVID-19 with general screening
strategy and encouraging people in Taiwan to wear a mask. Taiwan reported the first COVID-…

[HTML][HTML] Safety and immunogenicity of the M72/AS01E candidate tuberculosis vaccine in adults with tuberculosis: a phase II randomised study

P Gillard, PC Yang, M Danilovits, WJ Su, SL Cheng… - Tuberculosis, 2016 - Elsevier
Previous studies have shown that the M72/AS01 E candidate tuberculosis vaccine is
immunogenic with a clinically acceptable safety profile in healthy and Mycobacterium tuberculosis-…

Use of ICS/LABA combinations or LAMA is associated with a lower risk of acute exacerbation in patients with coexistent COPD and asthma

…, YH Tsai, DW Perng, WJ Su, KT Chou, KC Su… - The Journal of Allergy …, 2018 - Elsevier
Background Based on current guidelines, more research is urgently needed to guide
appropriate treatment for patients with asthma-chronic obstructive pulmonary disease (COPD) …

Microbiological Persistence in Patients With Mycobacterium avium Complex Lung Disease: The Predictors and the Impact on Radiographic Progression

…, JY Wang, YJ Chan, CJ Yu, WJ Su - Clinical Infectious …, 2017 - academic.oup.com
Background Persistent growth of Mycobacterium avium complex (MAC) in the lungs indicates
continuous infection in MAC lung disease (MAC-LD), but its clinical significance has not …

The risk of TB in patients with type 2 diabetes initiating metformin vs sulfonylurea treatment

…, PH Chuang, VYF Su, JY Feng, YJ Chan, WJ Su - Chest, 2018 - Elsevier
Background Metformin and the sulfonylureas are common initial antidiabetic agents; the former
has demonstrated anti-TB action in in vitro and animal studies. The comparative effect of …