The traditional view of p53 activation includes three steps—p53 stabilization, DNA binding,
and transcriptional activation. However, recent studies indicate that each step of p53 …

… For autosomal dominant genomic disorders that do not result in embryonic lethality and
are fully penetrant with fitness w, the per-locus per-generation rate (μ) of loss-of-function …

▪ Abstract Robust and bright light emitters, semiconductor nanocrystals [quantum dots (QDs)]
have been adopted as a new class of fluorescent labels. Six years after the first …

The Daya Bay Reactor Neutrino Experiment has measured a nonzero value for the neutrino
mixing angle θ 13 with a significance of 5.2 standard deviations. Antineutrinos from six 2.9 …

Eleven susceptibility loci for late-onset Alzheimer's disease (LOAD) were identified by previous
studies; however, a large portion of the genetic risk for this disease remains unexplained. …

Risk for late-onset Alzheimer’s disease (LOAD), the most prevalent dementia, is partially
driven by genetics. To identify LOAD risk loci, we performed a large genome-wide association …

… Derber, JC, and W.-S. Wu, 1998: The use of TOVS cloud-cleared radiances in the NCEP SSI
analysis system. … Fiedler, and W. Wimmer, 2012: The Operational Sea Surface Temperature …

… Membranes were blocked with 5% w/v non-fat dry milk and incubated with primary
antibodies overnight at 4 C and HRP-conjugated secondary antibodies (CST) for 2 h at room …

An outbreak of betacoronavirus severe acute respiratory syndrome (SARS)-CoV-2 began in
Wuhan, China in December 2019. COVID-19, the disease associated with SARS-CoV-2 …

Coronavirus disease 2019 (COVID-19), caused by the novel human coronavirus SARS-CoV-2,
is currently a major threat to public health worldwide. The viral spike protein binds the …