Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk

…, N Chaturvedi, TM Frayling, M Islam, TH Jafar… - Nature, 2011 - nature.com
Blood pressure is a heritable trait 1 influenced by several biological pathways and responsive
to environmental stimuli. Over one billion people worldwide have hypertension (≥140 mm …

Chronic kidney disease and cardiovascular risk: epidemiology, mechanisms, and prevention

…, R Correa-Rotter, BR Hemmelgarn, TH Jafar… - The Lancet, 2013 - thelancet.com
Since the first description of the association between chronic kidney disease and heart
disease, many epidemiological studies have confirmed and extended this finding. As chronic …

Chronic kidney disease

K Kalantar-Zadeh, TH Jafar, D Nitsch, BL Neuen… - The lancet, 2021 - thelancet.com
Chronic kidney disease is a progressive disease with no cure and high morbidity and mortality
that occurs commonly in the general adult population, especially in people with diabetes …

Progression of chronic kidney disease: the role of blood pressure control, proteinuria, and angiotensin-converting enzyme inhibition: a patient-level meta-analysis

TH Jafar, PC Stark, CH Schmid, M Landa… - Annals of internal …, 2003 - acpjournals.org
Background: Angiotensin-converting enzyme (ACE) inhibitors reduce blood pressure and
urine protein excretion and slow the progression of chronic kidney disease. Purpose: To …

Angiotensin-converting enzyme inhibitors and progression of nondiabetic renal disease: a meta-analysis of patient-level data

TH Jafar, CH Schmid, M Landa, I Giatras… - Annals of internal …, 2001 - acpjournals.org
Purpose: To examine the efficacy of ACE inhibitors for treatment of nondiabetic renal disease.
Data Sources: 11 randomized, controlled trials comparing the efficacy of antihypertensive …

Comparison of risk prediction using the CKD-EPI equation and the MDRD study equation for estimated glomerular filtration rate

…, BK Mahmoodi, M Woodward, JR Emberson, TH Jafar… - Jama, 2012 - jamanetwork.com
Context The Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI) equation more
accurately estimates glomerular filtration rate (GFR) than the Modification of Diet in Renal …

[HTML][HTML] Factors associated with psychological distress during the coronavirus disease 2019 (COVID-19) pandemic on the predominantly general population: A …

Y Wang, MP Kala, TH Jafar - PloS one, 2020 - journals.plos.org
Background The Coronavirus Disease 2019 (COVID-19) outbreak has escalated the burden
of psychological distress. We aimed to evaluate factors associated with psychological …

[HTML][HTML] Proteinuria as a modifiable risk factor for the progression of non-diabetic renal disease

TH Jafar, PC Stark, CH Schmid, M Landa, G Maschio… - Kidney international, 2001 - Elsevier
… Author links open overlay panel Tazeen H. Jafar , Paul C. Stark , Christopher … Jafar),
NEMC-St. Elizabeth's Medical Center Clinical Research Fellowship (Dr. …

Prevalence of overweight and obesity and their association with hypertension and diabetes mellitus in an Indo-Asian population

TH Jafar, N Chaturvedi, G Pappas - Cmaj, 2006 - Can Med Assoc
Background: The associations of body mass index (BMI) and chronic disease may differ
between Indo-Asian and Western populations. We used Indo-Asian-specific definitions of …

Cardiovascular disease, chronic kidney disease, and diabetes mortality burden of cardiometabolic risk factors from 1980 to 2010: a comparative risk assessment

…, BK Jacobsen, HY Jaddou, TH Jafar… - Lancet Diabetes & …, 2014 - observatorio.fm.usp.br
Background High blood pressure, blood glucose, serum cholesterol, and BMI are risk factors
for cardiovascular diseases and some of these factors also increase the risk of chronic …