User profiles for T. E. MacMillan
Thomas E. MacMillanAssistant Professor, University of Toronto Verified email at utoronto.ca Cited by 395 |
Desmopressin to prevent rapid sodium correction in severe hyponatremia: a systematic review
TE MacMillan, T Tang, RB Cavalcanti - The American Journal of Medicine, 2015 - Elsevier
Background Hyponatremia is common among inpatients and is associated with severe
adverse outcomes such as osmotic demyelination syndrome. Current guidelines recommend …
adverse outcomes such as osmotic demyelination syndrome. Current guidelines recommend …
The MedSafer study—electronic decision support for deprescribing in hospitalized older adults: a cluster randomized clinical trial
…, J Downar, AR Huang, TE MacMillan… - JAMA internal …, 2022 - jamanetwork.com
Importance Scalable deprescribing interventions may reduce polypharmacy and the use of
potentially inappropriate medications (PIMs); however, few studies have been large enough …
potentially inappropriate medications (PIMs); however, few studies have been large enough …
Prone positioning of patients with moderate hypoxaemia due to covid-19: multicentre pragmatic randomised trial (COVID-PRONE)
…, I Dhalla, R Dunbar-Yaffe, LB Day, TE MacMillan… - bmj, 2022 - bmj.com
Objectives To assess the effectiveness of prone positioning to reduce the risk of death or
respiratory failure in non-critically ill patients admitted to hospital with covid-19. Design …
respiratory failure in non-critically ill patients admitted to hospital with covid-19. Design …
Osmotic demyelination syndrome in patients hospitalized with hyponatremia
Background Osmotic demyelination syndrome (ODS) is a rare but potentially devastating
neurologic complication of hyponatremia. The primary objective of this study was to identify the …
neurologic complication of hyponatremia. The primary objective of this study was to identify the …
Outcomes in severe hyponatremia treated with and without desmopressin
TE MacMillan, RB Cavalcanti - The American Journal of Medicine, 2018 - Elsevier
Background Overcorrection of plasma sodium in severe hyponatremia is associated with
osmotic demyelination syndrome. Desmopressin (DDAVP) can prevent overcorrection of …
osmotic demyelination syndrome. Desmopressin (DDAVP) can prevent overcorrection of …
Derivation and validation of a novel risk score to predict overcorrection of severe hyponatremia: the Severe Hyponatremia Overcorrection Risk (SHOR) score
JD Woodfine, MM Sood, TE MacMillan… - Clinical Journal of the …, 2019 - journals.lww.com
Results A total of 623 patients presented with severe hyponatremia (mean initial value 112
mmol/L; SD 3.2). The prevalence of no, unlikely, possible, and definite overcorrection was 72…
mmol/L; SD 3.2). The prevalence of no, unlikely, possible, and definite overcorrection was 72…
[HTML][HTML] Principles for clinical care of patients with COVID-19 on medical units
• When considering how to structure medical care teams, it is important to consider how rapidly
teams can be scaled to need, their ability to integrate redeployed physicians and ensure …
teams can be scaled to need, their ability to integrate redeployed physicians and ensure …
[HTML][HTML] A journal club for peer mentorship: helping to navigate the transition to independent practice
TE MacMillan, S Rawal, P Cram, J Liu - Perspectives on Medical …, 2016 - Springer
… MacMillan’s work is supported financially by a fellowship from the HoPingKong Centre for …
TE MacMillan’s work is supported financially by a fellowship from the HoPingKong Centre for …
TE MacMillan’s work is supported financially by a fellowship from the HoPingKong Centre for …
Missed opportunity to deprescribe: docusate for constipation in medical inpatients
TE MacMillan, R Kamali, RB Cavalcanti - The American journal of medicine, 2016 - Elsevier
Background Hospital admissions provide an opportunity to deprescribe ineffective medications
and reduce pill burden. Docusate sodium is a stool softener that is frequently prescribed …
and reduce pill burden. Docusate sodium is a stool softener that is frequently prescribed …
[HTML][HTML] Melatonin for Insomnia in Medical Inpatients: A Narrative Review
In this narrative review, we describe what is known about non-pharmacological and
pharmacological treatments for insomnia in medical inpatients, with a focus on melatonin. Hospital-…
pharmacological treatments for insomnia in medical inpatients, with a focus on melatonin. Hospital-…