It is not understood how immune inflammation influences the pathogenesis of severe acute
respiratory syndrome (SARS). One area of strong controversy is the role of interferon (IFN) …

Background Severe Acute Respiratory Syndrome (SARS) became a global epidemic in
2003. Comprehensive information on 1-year outcomes and health care utilization is lacking. …

Verocytotoxin-producing Escherichia coli (VTEC) infection was present in three cases of
hemolytic uremic syndrome (HUS), two fatal and one non-fatal, in which detailed …

Objective. To describe mortality, morbidity at discharge and neurodevelopmental outcome at
2 years corrected age in extremely low birth weight infants with systemic Candida infection …

OBJECTIVE. The purpose of this study was to review the experience with herpes simplex
encephalitis at the Hospital for Sick Children over the past 12 years. METHODS. All patients …

Background Analysis of the population genetic structure of microbial species is of fundamental
importance to many scientific disciplines because it can identify cryptic species, reveal …

Urinary tract infections (UTIs) are a common occurrence in children. The management and
laboratory diagnosis of these infections pose unique challenges that are not encountered in …

Background: Influenza virus infection has been associated with a variety of neurologic
complications. The objective of this study was to evaluate prospectively the role of influenza …

Objectives: This study compared the sensitivity and specificity of culture and two nucleic
acid amplification tests (NAATs): the BD Probetec ET system (PT) and the Aptima Combo 2 (AC2…

Compared to DNA sequence analysis, matrix-assisted laser desorption ionization–time of
flight mass spectrometry (MALDI-TOF MS) correctly identified 100% of Cryptococcus species, …