User profiles for Stephen M. Hewitt

Stephen M Hewitt

Medical Officer, Laboratory of Pathology, National Cancer Institute
Verified email at helix.nih.gov
Cited by 41411

[HTML][HTML] SARS-CoV-2 infection of the oral cavity and saliva

…, JA Chiorini, DE Kleiner, S Pittaluga, SM Hewitt… - Nature medicine, 2021 - nature.com
Despite signs of infection—including taste loss, dry mouth and mucosal lesions such as
ulcerations, enanthema and macules—the involvement of the oral cavity in coronavirus disease …

[HTML][HTML] SARS-CoV-2 infection and persistence in the human body and brain at autopsy

…, JI Cohen, E de Wit, KM Vannella, SM Hewitt… - Nature, 2022 - nature.com
Coronavirus disease 2019 (COVID-19) is known to cause multi-organ dysfunction 1 , 2 – 3
during acute infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), …

Vitamin C pharmacokinetics: implications for oral and intravenous use

…, SM Hewitt, A Katz, RA Wesley, M Levine - Annals of internal …, 2004 - acpjournals.org
Background: Vitamin C at high concentrations is toxic to cancer cells in vitro. Early clinical
studies of vitamin C in patients with terminal cancer suggested clinical benefit, but 2 double-…

The membrane-cytoskeleton linker ezrin is necessary for osteosarcoma metastasis

…, A Mendoza, C Yeung, R Gorlick, SM Hewitt… - Nature medicine, 2004 - nature.com
Metastatic cancers, once established, are the primary cause of mortality associated with
cancer. Previously, we used a genomic approach to identify metastasis-associated genes in …

Renal tumors in the Birt-Hogg-Dube syndrome

…, MCM Walther, RA Eyler, SM Hewitt… - The American journal …, 2002 - journals.lww.com
Birt-Hogg-Dubé (BHD) syndrome is an autosomal dominant genodermatosis characterized
by the development of small dome-shaped papules on the face, neck, and upper trunk (…

Infrared spectroscopic imaging for histopathologic recognition

DC Fernandez, R Bhargava, SM Hewitt… - Nature biotechnology, 2005 - nature.com
The process of histopathology, comprising tissue staining and morphological pattern recognition,
has remained largely unchanged for over 140 years 1 . Although it is integral to clinical …

Antiangiogenic and antitumor effects of bevacizumab in patients with inflammatory and locally advanced breast cancer

…, CK Chow, P Choyke, D Danforth, SM Hewitt… - Journal of Clinical …, 2006 - ascopubs.org
Purpose Vascular endothelial growth factor (VEGF) is a potent molecule that mediates tumor
angiogenesis primarily through VEGF receptor 2 (VEGFR2). Bevacizumab, a recombinant …

Risk of renal and colonic neoplasms and spontaneous pneumothorax in the Birt-Hogg-Dube syndrome

…, MC Walther, P Choyke, G Weirich, SM Hewitt… - … Biomarkers & Prevention, 2002 - AACR
The Birt-Hogg-Dubé syndrome, a genodermatosis characterized by benign tumors of the
hair follicle, has been associated with renal and colonic neoplasms and spontaneous …

Differences in risk factors for breast cancer molecular subtypes in a population-based study

…, J Lissowska, LA Brinton, B Peplonska, SM Hewitt… - … Biomarkers & Prevention, 2007 - AACR
Abstract Analysis of gene expression data suggests that breast cancers are divisible into
molecular subtypes which have distinct clinical features. This study evaluates whether …

Post-analysis follow-up and validation of microarray experiments

…, CJM Best, JW Gillespie, MJ Flaig, SM Hewitt… - Nature …, 2002 - nature.com
Measurement of gene-expression profiles using microarray technology is becoming
increasingly popular among the biomedical research community. Although there has been great …