… , there is a lack of consensus on whether these astroglial tau pathologies in the elderly are
clinically relevant, even as a concomitant pathology that might lower an individual’s threshold …

Obesity, one of the most prevalent health problems in the Western world, is a chronic and
progressive condition. Therefore, as with other chronic diseases, patients with obesity require …

Astrocytes have essential roles in the central nervous system and are also implicated in the
pathogenesis of neurodegenerative disease. Forming non‐overlapping domains, astrocytes …

Background Obesity is a chronic disease that results in substantial global morbidity and
mortality. The efficacy and safety of tirzepatide, a novel glucose-dependent insulinotropic …

Background Obesity is a global health challenge with few pharmacologic options. Whether
adults with obesity can achieve weight loss with once-weekly semaglutide at a dose of 2.4 …

… Sean Wharton reports receiving honoraria and travel expenses and has participated in
academic advisory boards for Novo Nordisk, Bausch Health, Eli Lilly and Janssen. Sean Wharton …

… credit to the original author(s) and the source, provide a … ’s Creative Commons license,
unless indicated otherwise in a credit line to the material. If material is not included in the article’s …

Background Research in Alzheimer's disease is focused mainly on younger old persons,
whereas studies involving very old persons report attenuated relationships between the …

… , data were analyzed with the use of logistic regression; missing values were imputed
according to the multiple-imputation approach, and values were combined according to Rubin’s …

Background Obesity is a major public health issue, and new pharmaceuticals for weight
management are needed. Therefore, we evaluated the efficacy and safety of the glucagon-like …