User profiles for Rolf H.H. Groenwold

Rolf Groenwold

professor of Clinical Epidemiology, LUMC, Leiden University
Verified email at lumc.nl
Cited by 13850

Overestimation of risk ratios by odds ratios in trials and cohort studies: alternatives to logistic regression

…, A Algra, JP Vandenbroucke, RHH Groenwold - Cmaj, 2012 - Can Med Assoc
Analysis domly assigned to groups receiving surgery followed by radiotherapy, or radiotherapy
alone. 12 The primary outcome was the ability to walk, which occurred in 70.3% of the …

Missing covariate data in clinical research: when and when not to use the missing-indicator method for analysis

RHH Groenwold, IR White, ART Donders… - Cmaj, 2012 - Can Med Assoc
If missingness of a variable is related to observed characteristics but not to unobserved
characteristics, the data are (confusingly) called “missing at random.” 2, 5, 6 If data are missing at …

Get real in individual participant data (IPD) meta‐analysis: a review of the methodology

…, N Hummel, RHH Groenwold… - Research synthesis …, 2015 - Wiley Online Library
Individual participant data (IPD) meta‐analysis is an increasingly used approach for
synthesizing and investigating treatment effect estimates. Over the past few years, numerous …

Attributable mortality of ventilator-associated pneumonia: a meta-analysis of individual patient data from randomised prevention studies

WG Melsen, MM Rovers, RHH Groenwold… - The Lancet infectious …, 2013 - thelancet.com
Background Estimating attributable mortality of ventilator-associated pneumonia has been
hampered by confounding factors, small sample sizes, and the difficulty of doing relevant …

Estimating measures of interaction on an additive scale for preventive exposures

MJ Knol, TJ VanderWeele, RHH Groenwold… - European journal of …, 2011 - Springer
Measures of interaction on an additive scale (relative excess risk due to interaction [RERI],
attributable proportion [AP], synergy index [S]), were developed for risk factors rather than …

Dealing with missing outcome data in randomized trials and observational studies

RHH Groenwold, ART Donders… - American journal of …, 2012 - academic.oup.com
Although missing outcome data are an important problem in randomized trials and observational
studies, methods to address this issue can be difficult to apply. Using simulated data, …

Do self-management interventions work in patients with heart failure? An individual patient data meta-analysis

NH Jonkman, H Westland, RHH Groenwold, S Ågren… - Circulation, 2016 - Am Heart Assoc
Background— Self-management interventions are widely implemented in the care for patients
with heart failure (HF). However, trials show inconsistent results, and whether specific …

Operative treatment versus nonoperative treatment of Achilles tendon ruptures: systematic review and meta-analysis

…, M Heng, O van der Meijden, RHH Groenwold… - Bmj, 2019 - bmj.com
Objectives To compare re-rupture rate, complication rate, and functional outcome after
operative versus nonoperative treatment of Achilles tendon ruptures; to compare re-rupture rate …

Reporting of covariate selection and balance assessment in propensity score analysis is suboptimal: a systematic review

MS Ali, RHH Groenwold, SV Belitser… - Journal of clinical …, 2015 - Elsevier
Objectives To assess the current practice of propensity score (PS) analysis in the medical
literature, particularly the assessment and reporting of balance on confounders. Study Design …

Performance of the original EuroSCORE

S Siregar, RHH Groenwold, F de Heer… - European journal of …, 2012 - academic.oup.com
The European system for cardiac operative risk evaluation (EuroSCORE) is a commonly
used risk score for operative mortality following cardiac surgery. We aimed to conduct a …