Methods The review group decided that a more explicit and structured approach (figure) to
the process of developing recommendations was required to address the weaknesses …

Background Osteoporosis is a condition resulting in an increased risk of skeletal fractures
due to a reduction in the density of bone tissue. Treatment of osteoporosis typically involves …

Background: Although several tools to evaluate the credibility of health care guidelines exist,
guidance on practical steps for developing guidelines is lacking. We systematically …

Background Systems that are used by different organisations to grade the quality of evidence
and the strength of recommendations vary. They have different strengths and weaknesses. …

OBJECTIVES: In this article, we describe how to include considerations about resource
utilization when making recommendations according to the Grading of Recommendations …

Background Healthcare decision makers face challenges when using guidelines, including
understanding the quality of the evidence or the values and preferences upon which …

Background Clinical practice guidelines are typically written for healthcare providers but
there is increasing interest in producing versions for the public, patients and carers. The main …

Background Guideline producers are increasingly producing versions of guidelines for the
public. The aim of this study was to explore what patients and the public understand about the …

Background Approximately half of the world’s population is infected with Helicobacter pylori
(H.pylori), a bacterium shown to be linked with a series of gastrointestinal diseases. A …

Background. Evidence-based clinical guidelines could support shared decision-making and
help patients to participate actively in their care. However, it is not well known how patients …