The 5-point Investigator's Global Assessment (IGA) Scale: a modified tool for evaluating plaque psoriasis severity in clinical trials

RGB Langley, SR Feldman, J Nyirady… - Journal of …, 2015 - Taylor & Francis
Background: To evaluate new psoriasis treatments, clinicians, regulators and pharmaceutical
developers require well-accepted, clinically meaningful measures of disease severity. The …

[HTML][HTML] Apremilast, an oral phosphodiesterase 4 (PDE4) inhibitor, in patients with moderate to severe plaque psoriasis: results of a phase III, randomized, controlled …

…, L Kircik, S Chimenti, RGB Langley… - Journal of the American …, 2015 - Elsevier
… Dr Langley has served as an investigator for Abbott, Amgen, Centocor, Celgene, Pfizer,
Johnson & Johnson/Ortho Biotech, and Novartis; as a speaker for Abbott, Amgen, Centocor, …

Safety and efficacy of pimecrolimus (ASM 981) cream 1% in the treatment of mild and moderate atopic dermatitis in children and adolescents

…, AW Lucky, M Boguniewiczc, RGB Langley… - Journal of the American …, 2002 - Elsevier
Background: The ascomycin derivative pimecrolimus (ASM 981) is a cell-selective cytokine
inhibitor, specifically developed for the treatment of inflammatory skin diseases. Objective: …

Automatic differentiation of melanoma from melanocytic nevi with multispectral digital dermoscopy: a feasibility study

…, AW Kopf, HS Rabinovitz, RGB Langley… - Journal of the American …, 2001 - Elsevier
Background: Differentiation of melanoma from melanocytic nevi is difficult even for skin
cancer specialists. This motivates interest in computer-assisted analysis of lesion images. …

Confocal scanning laser microscopy of benign and malignant melanocytic skin lesions in vivo

RGB Langley, M Rajadhyaksha, PJ Dwyer… - Journal of the American …, 2001 - Elsevier
Background: The ability of physicians for early diagnosis of cutaneous melanomas is less
than perfect, prompting research into noninvasive methods for diagnosis. Objective: Our …

The diagnostic accuracy of in vivo confocal scanning laser microscopy compared to dermoscopy of benign and malignant melanocytic lesions: a prospective study

RGB Langley, N Walsh, AE Sutherland, I Propperova… - Dermatology, 2007 - karger.com
Background: The diagnosis of melanoma at an early, curable stage is an important
challenge for clinicians. Confocal scanning laser microscopy (CSLM) is a high-resolution, …

Weight change and adverse event incidence with a low-dose oral contraceptive: two randomized, placebo-controlled trials

PJ Coney, K Washenik, RGB Langley, JJ DiGiovanna… - Contraception, 2001 - Elsevier
Changes in body weight and the incidence of estrogen-related side effects with low-dose oral
contraceptives (OCs) containing 20 μg ethinyl estradiol (EE) have not been demonstrated …

In vivo confocal scanning laser microscopy of benign lentigines: comparison to conventional histology and in vivo characteristics of lentigo maligna

RGB Langley, E Burton, N Walsh, I Propperova… - Journal of the American …, 2006 - Elsevier
BACKGROUND: An important challenge facing clinicians is recognizing and distinguishing
benign pigmented lesions from cutaneous melanoma. Lentigines are a type of benign …

Multiple eruptive milia: report of a case, review of the literature, and a classification

RGB Langley, NMG Walsh, JB Ross - Journal of the American Academy of …, 1997 - Elsevier
A 71-year-old man presented with an acute onset of multiple white papules on the face and
chest. Histologic sections demonstrated multiple milia. The rare condition of multiple eruptive …

A clinical review of the evidence for the role of ultraviolet radiation in the etiology of cutaneous melanoma

RGB Langley, AJ Sober - Cancer investigation, 1997 - Taylor & Francis
INTRODUCTION The incidence of cutaneous melanoma is increasing at a greater rate than
any other malignancy in men and is second only to lung cancer in women (1). In the United …