Background Warfarin reduces the risk of stroke in patients with atrial fibrillation but increases
the risk of hemorrhage and is difficult to use. Dabigatran is a new oral direct thrombin …

Background Vitamin K antagonists are highly effective in preventing stroke in patients with
atrial fibrillation but have several limitations. Apixaban is a novel oral direct factor Xa inhibitor …

OBJECTIVE. We examined specific family rejecting reactions to sexual orientation and gender
expression during adolescence as predictors of current health problems in a sample of …

Background Vitamin K antagonists have been shown to prevent stroke in patients with atrial
fibrillation. However, many patients are not suitable candidates for or are unwilling to receive …

ISSUE: The role of family acceptance as a protective factor for lesbian, gay, bisexual, and
transgender (LGBT) adolescents and young adults has not been established. METHODS: A …

Background Patients who have had an acute coronary syndrome are at high risk for recurrent
ischemic cardiovascular events. We sought to determine whether alirocumab, a human …

Background Mineralocorticoid-receptor antagonists improve the prognosis for patients with
heart failure and a reduced left ventricular ejection fraction. We evaluated the effects of …

Background Cardiovascular morbidity and mortality are higher among patients with type 2
diabetes, particularly those with concomitant cardiovascular diseases, than in most other …

Background We evaluated whether rivaroxaban alone or in combination with aspirin would
be more effective than aspirin alone for secondary cardiovascular prevention. Methods In this …

Importance Hypertension is the most important preventable cause of morbidity and mortality
globally, yet there are relatively few data collected using standardized methods. Objective …