This article concerns development and use of patient-reported outcomes (PROs) in clinical
trials to evaluate medical products. A PRO is any report coming directly from patients, without …

… We start with a simple admittance matrix defined by resistance, r, and reactance, x. We
assume shunt susceptance is negligible. The elements of G, B and Y matrices are derived as …

… We also recognize Bob O’Neill for his contributions to the first edition and for many great
years of collaborative research at Oak Ridge National Laboratory (ORNL). At the time when …

Since its initial release in 2000, the human reference genome has covered only the
euchromatic fraction of the genome, leaving important heterochromatic regions unfinished. …

The services of ecological systems and the natural capital stocks that produce them are
critical to the functioning of the Earth's life-support system. They contribute to human welfare, …

… As analyses move to larger scales, it becomes necessary to deal with new phenomena that
arise at these levels (O'Neill et al. Allen et al. The spatial patterning of ecosystem types is a …

Niemann-Pick type C (NP-C) disease, a fatal neurovisceral disorder, is characterized by
lysosomal accumulation of low density lipoprotein (LDL)–derived cholesterol. By positional …

… Although still relying on lumping distinct biological entities, O'Neill's grouping is based primarily
on functional roles in the system. The nutrient retention component is specifically defined …

While searching for alternative reading-frame peptides encoded by influenza A virus that are
recognized by CD8 + T cells, we found an abundant immunogenic peptide encoded by the …

… Since a1 - d1 and g1 are closely related to the so called "r" and "K" parameters, respectively,
connections can be drawn between our results and the extensive body of knowledge on r …