Role of extracellular matrix proteins in heart function
V Pelouch, IMC Dixon, L Golfman, RE Beamish… - Molecular and cellular …, 1993 - Springer
The cardiac interstitium is populated by nonmyocyte cell types including transcriptionally
active cardiac fibroblasts and endothelial cells. Since these cells are the source of many …
active cardiac fibroblasts and endothelial cells. Since these cells are the source of many …
Calcium movements in relation to heart function
…, GN Pierce, V Panagia, PK Singal, RE Beamish - Basic research in …, 1982 - Springer
It is widely recognized that calcium is of singular importance in the viability of the myocardial
cell, nonetheless little is known concerning the precise nature of the action of calcium in …
cell, nonetheless little is known concerning the precise nature of the action of calcium in …
Potential oxidative pathways of catecholamines in the formation of lipid peroxides and genesis of heart disease
PK Singal, RE Beamish, NS Dhalla - Myocardial injury, 1983 - Springer
… Effects of isoproterenol and vitamin E treatment on the malondialdehyde (MDA) content
in the heart were determined and the results are shown in Fig. 2. There was a significant …
in the heart were determined and the results are shown in Fig. 2. There was a significant …
Pathogenesis of cardiac dysfunction in diabetes mellitus.
…, GN Pierce, IR Innes, RE Beamish - The Canadian journal of …, 1985 - europepmc.org
The use of insulin by diabetics has largely removed the threat of death from ketotic coma but
cardiovascular dysfunction remains a major cause of death in patients with diabetes. …
cardiovascular dysfunction remains a major cause of death in patients with diabetes. …
Pathophysiology of cardiac dysfunction in congestive heart failure.
NS Dhalla, N Afzal, RE Beamish, B Naimark… - The Canadian journal …, 1993 - europepmc.org
Although various factors, such as myocardial infarction, pressure overload and volume
overload, result in the development of congestive heart failure (CHF), the pathogenesis of …
overload, result in the development of congestive heart failure (CHF), the pathogenesis of …
Depression of heart sarcolemmal Ca2+-pump activity by oxygen free radicals
M Kaneko, RE Beamish… - American Journal of …, 1989 - journals.physiology.org
… BEAMISH, AND NARANJAN S. DHALLA. Depression of heart sarcolemmal Ca2+-pump …
Recently, it has been shown that Na+-K+-ATPase activity of cardiac sarcolemmal membrane …
Recently, it has been shown that Na+-K+-ATPase activity of cardiac sarcolemmal membrane …
Ventricular dysfunction and necrosis produced by adrenochrome metabolite of epinephrine: relation to pathogenesis of catecholamine cardiomyopathy
JC Yates, RE Beamish, NS Dhalla - American heart journal, 1981 - Elsevier
We have examined the effects of adrenochrome and other metabolites of epinephrine on
the ultrastructure and contractile activity of isolated rat hearts perfused under conditions in …
the ultrastructure and contractile activity of isolated rat hearts perfused under conditions in …
Cardiac alpha-and beta-adrenergic receptor alterations in diabetic cardiomyopathy
…, GN Pierce, PK Singal, RE Beamish… - Basic research in …, 1982 - Springer
The effect of chronic experimental diabetes on the adrenergic receptors in the rat heart was
investigated. Diabetes was induced by streptozotocin (65 mg/kg; iv) administration, animals …
investigated. Diabetes was induced by streptozotocin (65 mg/kg; iv) administration, animals …
Norepinephrine storage, distribution, and release in diabetic cardiomyopathy
PK Ganguly, RE Beamish, KS Dhalla… - American Journal …, 1987 - journals.physiology.org
The ability of hearts to store, distribute, and release norepinephrine (NE) was investigated
in rats 8 wk after the induction of diabetes by an injection of streptozotocin (65 mg/kg iv). …
in rats 8 wk after the induction of diabetes by an injection of streptozotocin (65 mg/kg iv). …
Altered norepinephrine turnover and metabolism in diabetic cardiomyopathy.
PK Ganguly, KS Dhalla, IR Innes, RE Beamish… - Circulation …, 1986 - Am Heart Assoc
… NE and have suggested some disturbance of NE release in diabetic hearts. However, NE …
Experiments were undertaken to examine if changes in cardiac NE concentration are re…
Experiments were undertaken to examine if changes in cardiac NE concentration are re…