We hypothesized that regular use of long-acting β -agonists could delay recognition of (“mask”)
increasing airway inflammation. We studied steroid-sparing and “masking” effects of …

Background: It is unclear whether asthma is overdiagnosed in developed countries, particularly
among obese individuals, who may be more likely than nonobese people to experience …

Importance Although asthma is a chronic disease, the expected rate of spontaneous
remissions of adult asthma and the stability of diagnosis are unknown. Objective To determine …

… J Mark FitzGerald MD FRCPC1, Louis-Philippe Boulet MD FRCPC2, R Andrew McIvor
MD FRCPC3, Sabrina Zimmerman BSc4, Kenneth R Chapman MD MSc FRCPC5 …

The respiratory rate is a vital sign with an underappreciated significance that can, in acute
situations, prognosticate patients’ mortality rate and need for invasive ventilation. In addition, …

Objective The objectives of our study were to compare patient characteristics and severity of
disease in obese and normal-weight-confirmed people with asthma and to explore reasons …

Review spirometry results or with symptoms uncharacteristic of asthma. Airway hyperresponsiveness
is usually measured using direct stimuli, such as methacholine or histamine, that …

Atovaquone suspensions (750 mg and 1500 mg once a day) were compared with
aerosolized pentamidine (300 mg once a month) for the prevention of Pneumocystis carinii …

BACKGROUND: In patients with asthma, smoking has been associated with accelerated
decline in pulmonary function, poor disease control and reduced responsiveness to …

Background In patients with a history suggestive of asthma, diagnosis is usually confirmed
by spirometry with bronchodilator response (BDR) or confirmatory methacholine challenge …