Genetic variation among individual humans occurs on many different scales, ranging from
gross alterations in the human karyotype to single nucleotide changes. Here we explore …

Despite considerable excitement over the potential functional significance of copy-number
variants (CNVs), we still lack knowledge of the fine-scale architecture of the large majority of …

Array-based comparative genomic hybridization (CGH) measures copy-number variations
at multiple loci simultaneously, providing an important tool for studying cancer and …

The adhesion of bacteria to surfaces plays critical roles in the environment, disease, and
industry. In aquatic environments, Caulobacter crescentus is one of the first colonizers of …

The discovery of copy number variation in healthy individuals is far from complete, and owing
to the resolution of detection systems used, the majority of loci reported so far are relatively …

Randomized controlled trials have shown a reduction in platelet alloimmunization and
refractoriness in patients with acute leukemia (AL) with the use of poststorage leukoreduction of …

Prader–Willi syndrome (PWS) and Angelman syndrome (AS) are oppositely imprinted
autism-spectrum disorders with known genetic bases, but complex epigenetic mechanisms …

We report a novel and fast method for converting a digital, complex Fresnel hologram into a
phase-only hologram. Briefly, the pixels in the complex hologram are scanned sequentially …

The extent of human genomic structural variation suggests that there must be portions of the
genome yet to be discovered, annotated and characterized at the sequence level. We …

Prader–Willi syndrome (PWS), a genetic disorder of obesity, intellectual disability and sleep
abnormalities, is caused by loss of non-coding RNAs on paternal chromosome 15q11-q13. …