We describe a platform for context-aware computing which enables applications to follow
mobile users as they move around a building. The platform is particularly suitable for richly …

We have been able to convert a small α/β protein, acylphosphatase, from its soluble and
native form into insoluble amyloid fibrils of the type observed in a range of pathological …

Protozoan parasites of the phylum Apicomplexa contain three genetic elements: the nuclear
and mitochondrial genomes characteristic of virtually all eukaryotic cells and a 35-kilobase …

In the face of a surge in cases of coronavirus disease 2019 (COVID-19), physicians and health
systems worldwide are racing to adopt virtualised treatment approaches that obviate the …

Adenoviruses enter their host cells by receptor-mediated endocytosis and acid-activated
penetration from endosomes into the cytosol and deliver their DNA genome into the nucleus. …

Objective: This study addresses three questions: 1) What are the clinical presentations of
pancreatitis secondary to hyperlipidemia? 2) What is the role of alcohol, diabetes, or known …

PEGylated gold nanoparticles are decorated with various amounts of human transferrin (Tf)
to give a series of Tf-targeted particles with near-constant size and electrokinetic potential. …

In vitro studies of non-viral gene delivery vectors are typically not performed at physiological
conditions, and thus may not provide meaningful results for in vivo investigations. We …

rab4 is a ras-like GTP-binding protein that associates with early endosomes in a cell cycle-dependent
fashion. To determine its role during endocytosis, we generated stable cell lines …

Lysosomes are considered to be a terminal degradative compartment of the endocytic
pathway, into which transport is mostly unidirectional. However, specialized secretory vesicles …