Prospective validation of a 1-hour algorithm to rule-out and rule-in acute myocardial infarction using a high-sensitivity cardiac troponin T assay

…, P Hillinger, C Jäger, T Herrmann, P Kreutzinger… - Cmaj, 2015 - Can Med Assoc
Background: We aimed to prospectively validate a novel 1-hour algorithm using high-sensitivity
cardiac troponin T measurement for early rule-out and rule-in of acute myocardial …

Misdiagnosis of myocardial infarction related to limitations of the current regulatory approach to define clinical decision values for cardiac troponin

…, P Haaf, P Hillinger, N Schaerli, P Kreutzinger… - Circulation, 2015 - Am Heart Assoc
… -term mortality comparable to that of patients with consistent diagnoses (P=NS) and a
trend toward higher long-term mortality than patients diagnosed with unstable angina (P=0.05). …

One-hour rule-in and rule-out of acute myocardial infarction using high-sensitivity cardiac troponin I

…, C Schumacher, ZM Weidmann, P Kreutzinger… - American heart …, 2016 - Elsevier
Objective We aimed to prospectively derive and validate a novel 0-/1-hour algorithm using
high-sensitivity cardiac troponin I (hs-cTnI) for the early “rule-out” and “rule-in” of acute …

Safety and efficacy of the 0 h/3 h protocol for rapid rule out of myocardial infarction

…, C Jaeger, I Campodarve, P Kreutzinger… - American heart …, 2016 - Elsevier
Background The early and accurate diagnosis of acute myocardial infarction (AMI) is an
important medical and economic challenge. We aimed to prospectively evaluate the …

Clinical benefit of high-sensitivity cardiac troponin I in the detection of exercise-induced myocardial ischemia

…, P Kreutzinger, F Stallone, P Hillinger… - American heart …, 2016 - Elsevier
… High-sensitivity cTnI levels were significantly higher at all time points in patients with myocardial
ischemia as compared with those without (P < .001 for all). Combining clinical judgment …

[HTML][HTML] Early rule-out and rule-in of myocardial infarction using sensitive cardiac Troponin I

…, C Schumacher, V Delfine, P Kreutzinger… - International journal of …, 2015 - Elsevier
… All hypothesis testing was two-tailed and p-value of less than 0.05 was considered statistically
significant. All statistical analyses were performed using SPSS for Windows 21.0 (SPSS …

Incremental value of a single high-sensitivity cardiac troponin I measurement to rule out myocardial ischemia

…, P Kreutzinger, G Pretre, F Stallone, P Hillinger… - The American journal of …, 2015 - Elsevier
… < .001) and remained an independent predictor of ischemia in multivariable analysis (P < .…
(P < .001), which also tended to be superior to clinical judgment after exercise testing (0.69, P

Prevalence, characteristics and outcome of non-cardiac chest pain and elevated copeptin levels

…, N Fuechslin, P Hillinger, C Jaeger, P Kreutzinger… - Heart, 2014 - heart.bmj.com
Objective Copeptin, a quantitative marker of endogenous stress, seems to provide incremental
value in addition to cardiac troponin in the early rule-out of acute myocardial infarction (…

Ventricular conduction abnormalities as predictors of long‐term survival in acute de novo and decompensated chronic heart failure

…, D Marono, J Parenica, P Kreutzinger… - ESC heart …, 2016 - Wiley Online Library
… ventricular conduction (57.0%); P < 0.001 for both. The impact of … In all analyses, P-values
<0.05 were regarded as statistically … P-value for difference between groups by log-rank test. …

Effects of hemolysis on the diagnostic accuracy of cardiac troponin I for the diagnosis of myocardial infarction

…, K Grimm, P Kreutzinger… - International …, 2015 - internationaljournalofcardiology.com
Acute myocardial infarction (AMI) is among the leading causes of death worldwide [1].
Measurement of cardiac troponin (cTn) T or I currently form one of the cornerstones in the …