Overwhelming evidence shows the quality of reporting of randomised controlled trials (RCTs)
is not optimal. Without transparent reporting, readers cannot judge the reliability and …

… We interpreted P≤.05 as indicating statistical significance; all P values are 2-sided. When
reporting results from individual studies, we cited the measures of association and P values …

Background: Guidelines exist for the surgical treatment of hip fracture, but the effect of early
surgery on mortality and other outcomes that are important for patients remains unclear. We …

Systematic reviews and meta-analyses are essential to summarize evidence relating to
efficacy and safety of health care interventions accurately and reliably. The clarity and …

GRADE suggests that examination of 95% confidence intervals (CIs) provides the optimal
primary approach to decisions regarding imprecision. For practice guidelines, rating down the …

Background There is substantial variability in the perioperative administration of aspirin in
patients undergoing noncardiac surgery, both among patients who are already on an aspirin …

Background The relative benefits and risks of performing coronary-artery bypass grafting (CABG)
with a beating-heart technique (off-pump CABG), as compared with cardiopulmonary …

… We reported adjusted odds ratios and associated 95% CIs and P values. We tested the
trend of … We set the criterion for statistical significance at P value less than 0.05 for all tests. …

… We regarded p values of less than 0·05 as significant. We used SAS statistical package (…
patients than in poor patients, (p<0·0001), and angiography rates were also higher (p<0·0001). …

ContextRandomized clinical trials (RCTs) that stop earlier than planned because of apparent
benefit often receive great attention and affect clinical practice. Their prevalence, the …