Background: The recent outbreaks of avian influenza (H5N1) have placed a renewed
emphasis on preparing for an influenza pandemic in humans. Of particular concern in this …

Background: Internal hospital transfer is a vulnerable time during which patients are at high
risk of medication discrepancies that can result in clinically significant harm, medication …

Despite continuing controversies regarding the vital status of both brain-dead donors and
individuals who undergo donation after circulatory death (DCD), respecting the dead donor …

Objectives: Antimicrobial stewardship is advocated to reduce antimicrobial resistance in ICUs
by reducing unnecessary antimicrobial consumption. Evidence has been limited to short, …

Introduction The objective of this pilot study was to assess the usability of the draft Ontario
triage protocol, to estimate its potential impact on patient outcomes, and ability to increase …

To study the effect of increases in lung volume on solute uptake, we measured clearance of
99mTc-diethylenetriaminepentaacetic acid (Tc-DTPA) at different lung volumes in 19 healthy …

BRAIN DEATH IS DEFINED AS THE COMPLETE AND IRREVERSIBLE absence of all brain
function. It is diagnosed by means of rigorous testing at the bedside. The advent of …

Abstract Setting treatment goals in the intensive care unit (ICU) often involves resuscitation
decisions. Our objective was to study the rate of establishing do-not-resuscitate (DNR) …

Background Most critically ill patients are incapable of providing informed consent for research.
Objective We sought to determine patients’ preferences for different consent frameworks …

Substitute decision-making is a means of making health care decisions on behalf of people
who are incapable of making these decisions for themselves. It is based on the ethical …