The ability of skeletal muscles to produce force at a high velocity, which is crucial for
success in power and sprint performance, is strongly influenced by genetics and without the …

Over time, the human DNA methylation landscape accrues substantial damage, which has
been associated with a broad range of age-related diseases, including cardiovascular …

… (H, I, J, K, S, T, U, V, W, etc.) belong to macrohaplogroup N, whereas Asian haplogroups
belong to both macrohaplogroups N and M (haplogroups A, B, F, and N9a to macrohaplogroup …

The general consensus among sport and exercise genetics researchers is that genetic tests
have no role to play in talent identification or the individualised prescription of training to …

Background To date, studies investigating the association between ACTN3 R577X and ACE
I/D gene variants and elite sprint/power performance have been limited by small cohorts …

Hand grip strength is a widely used proxy of muscular fitness, a marker of frailty, and predictor
of a range of morbidities and all-cause mortality. To investigate the genetic determinants of …

A common genetic variation in the α-actinin-3 (ACTN3) gene causes a replacement of an
arginine (R) with a premature stop codon (X) at amino-acid 577 (rs1815739). While the R allele …

The response to exercise training (trainability) has been shown to have a strong heritable
component. There is growing evidence suggesting that traits such as trainability do not only …

There are strong genetic components to cardiorespiratory fitness and its response to exercise
training. It would be useful to understand the differences in the genomic profile of highly …

Despite numerous attempts to discover genetic variants associated with elite athletic
performance, injury predisposition, and elite/world-class athletic status, there has been limited …