Background To determine whether a restrictive strategy of red-cell transfusion and a liberal
strategy produced equivalent results in critically ill patients, we compared the rates of death …

Background Antifibrinolytic agents are commonly used during cardiac surgery to minimize
bleeding and to reduce exposure to blood products. We sought to determine whether …

As the risks of allogeneic blood transfusion (ABT)–transmitted viruses were reduced to
exceedingly low levels in the US, transfusion-related acute lung injury (TRALI), hemolytic …

Allogeneic blood transfusion (ABT)-related immunomodulation (TRIM) encompasses the
laboratory immune aberrations that occur after ABT and their established or purported clinical …

… Blajchman MA: Transfusion-associated immunomodulation and universal white cell
reduction: Are we putting the cart before the horse? Transfusion 1999; 39: 665–670 …

Background Fresh red cells may improve outcomes in critically ill patients by enhancing
oxygen delivery while minimizing the risks of toxic effects from cellular changes and the …

OBJECTIVE: To determine whether extremely low birth weight infants (ELBW) transfused at
lower hemoglobin thresholds versus higher thresholds have different rates of survival or …

Allogeneic blood transfusion results in the infusion into the recipient of large amounts of foreign
antigens in both soluble and cell-associated forms. The persistence of these antigens in …

A considerable literature has accumulated over the past decade indicating that leukocytes
present in allogeneic cellular blood components, intended for transfusion, are associated with …

Background Some observational studies have reported that transfusion of red-cell units that
have been stored for more than 2 to 3 weeks is associated with serious, even fatal, adverse …