[HTML][HTML] 5-fluorouracil resistant colon cancer cells are addicted to OXPHOS to survive and enhance stem-like traits

…, ML Taddei, E Giannoni, S Kopetz, SMA Kazmi… - Oncotarget, 2015 - ncbi.nlm.nih.gov
Despite marked tumor shrinkage after 5-FU treatment, the frequency of colon cancer relapse
indicates that a fraction of tumor cells survives treatment causing tumor recurrence. The …

A phase 1b multitumor cohort study of cabozantinib plus atezolizumab in advanced solid tumors (COSMIC-021): Results of the colorectal cancer cohort.

TA Abrams, SMA Kazmi, IS Winer, V Subbiah… - 2022 - ascopubs.org
121 Background: Cabozantinib, a multiple receptor tyrosine kinase inhibitor, promotes an
immune-permissive environment which may enhance the activity of immune checkpoint …

Age-dependent prognostic value of KRAS mutation in metastatic colorectal cancer

…, NN Sanford, C Ahn, MS Beg, SM Ali Kazmi - Future …, 2021 - Future Medicine
Background: The age-dependent prognostic impact of KRAS status in metastatic colorectal
cancer (mCRC) is unknown. Materials & Methods: We used the National Cancer Database to …

Preliminary safety and efficacy of tinengotinib tablets as monotherapy and combination therapy in advanced solid tumors: A phase Ib/II clinical trial.

…, S Goel, CY Liao, NY Gabrail, F Dayyani, SMA Kazmi… - 2023 - ascopubs.org
3019 Background: Tinengotinib is a spectrum-selective multi-kinase inhibitor that targets cell
proliferation, angiogenesis, and immune-oncology pathways by inhibiting Aurora kinases A/…

[HTML][HTML] Distinct clinical characteristics in young-onset pancreatic neuroendocrine tumor

SY Goksu, M Ozer, SMA Kazmi, NN Sanford… - Cancers, 2020 - mdpi.com
Simple Summary The impact of age and socioeconomic factors on the outcomes of patients
with pancreatic neuroendocrine tumors is understudied. In this study, we investigated the …

[HTML][HTML] Clinical, pathological, and adjuvant chemotherapy use differences among microsatellite unstable and microsatellite stable colon cancers

…, R Nair, N Sanford, J Su, E Huang, SMA Kazmi - Journal of the National …, 2024 - Elsevier
Background Colon cancers are categorized into mismatch repair deficient/microsatellite
unstable (MSI-H) and mismatch repair proficient/microsatellite stable (MSS) cancers. This study …

[HTML][HTML] Epstein-Barr virus EBER transcripts affect miRNA-mediated regulation of specific targets and are processed to small RNA species

J Alles, D Hasler, SMA Kazmi, M Tesson, A Hamilton… - Non-coding RNA, 2015 - mdpi.com
The oncogenic Epstein-Barr virus (EBV) expresses 44 mature microRNAs and two non-coding
EBER RNAs of 167 (EBER1) and 172 (EBER2) nt length. MiRNA profiling of NK/T cell …

Neutrophil-to-lymphocyte ratio and clinical outcomes in liver resection for metastatic colorectal cancer.

…, S Al Mutar, R Kainthla, E Huang, SMA Kazmi - 2023 - ascopubs.org
233 Background: The neutrophil-to-lymphocyte ratio (NLR) has been shown to correlate
with overall and disease-free survival in patients with colorectal cancer. The data about …

Heterogeneity of acquired KRAS and EGFR mutations in colorectal cancer patients treated with anti-EGFR monoclonal antibodies.

MP Morelli, MJ Overman, A Dasari, SMA Kazmi… - 2013 - ascopubs.org
3512 Background: Although KRAS and EGFR extracellular domain acquired mutations
were detected in two small cohorts and correlated with acquired resistance to anti-EGFR …

[BOOK][B] Textbook of special education

SSH Kazmi, M Ali - 2021 - books.google.com
“Disabled children are equally entitled to an exciting and brilliant future”-Nelson Mandela
Special Education is a need based, target specific approach to teach and train the children …