Background. The number of diseases and physical functioning difficulties tend to increase
with age. The aim of this study was to examine the trajectories of physical functioning across …

Title. What degree of work overload is likely to cause increased sickness absenteeism among
nurses? Evidence from the RAFAELA patient classification system Aim. This paper reports …

Background Multimorbidity is increasingly common and is associated with adverse health
outcomes, highlighting the need to broaden the single-disease framework that dominates …

Objectives Observational studies suggest that high job strain is a risk factor for retirement on
health grounds, but few studies have analysed specific diagnoses. We examined job strain's …

Background The number of individuals living with dementia is increasing, negatively affecting
families, communities, and health-care systems around the world. A successful response …

Approaches exploiting trait distribution extremes may be used to identify loci associated
with common traits, but it is unknown whether these loci are generalizable to the broader …

Objectives This study focused on estimating the relative risk of coronary heart disease (CHD)
in association with work stress, as indicated by the job-strain model, the effort-reward …

Background Published work assessing psychosocial stress (job strain) as a risk factor for
coronary heart disease is inconsistent and subject to publication bias and reverse causation …

Prediabetes (intermediate hyperglycaemia) is a high-risk state for diabetes that is defined
by glycaemic variables that are higher than normal, but lower than diabetes thresholds. 5–10% …

Cumulative meta-analyses are used to evaluate the extent to which further studies are
needed to confirm or refute a hypothesis. We used this approach to assess observational …