User profiles for Melis N. Anahtar
 | Melis Nuray AnahtarPost-doctoral research fellow at the Broad Institute of MIT and Harvard, MGH Verified email at mgh.harvard.edu Cited by 2614 |
Applications of machine learning to the problem of antimicrobial resistance: an emerging model for translational research
Antimicrobial resistance (AMR) remains one of the most challenging phenomena of modern
medicine. Machine learning (ML) is a subfield of artificial intelligence that focuses on the …
medicine. Machine learning (ML) is a subfield of artificial intelligence that focuses on the …
Phylogenetic analysis of SARS-CoV-2 in Boston highlights the impact of superspreading events
INTRODUCTION We used genomic epidemiology to investigate the introduction and spread
of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in the Boston area …
of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in the Boston area …
Discovery of a structural class of antibiotics with explainable deep learning
The discovery of novel structural classes of antibiotics is urgently needed to address the
ongoing antibiotic resistance crisis 1 , 2 , 3 , 4 , 5 , 6 , 7 , 8 – 9 . Deep learning approaches have …
ongoing antibiotic resistance crisis 1 , 2 , 3 , 4 , 5 , 6 , 7 , 8 – 9 . Deep learning approaches have …
[HTML][HTML] Clinical sensitivity and interpretation of PCR and serological COVID‐19 diagnostics for patients presenting to the hospital
…, AZ Bard, T Gogakos, MN Anahtar… - The FASEB …, 2020 - ncbi.nlm.nih.gov
The diagnosis of COVID‐19 requires integration of clinical and laboratory data. Severe acute
respiratory syndrome coronavirus 2 (SARS‐CoV‐2) diagnostic assays play a central role in …
respiratory syndrome coronavirus 2 (SARS‐CoV‐2) diagnostic assays play a central role in …
Structural topology defines protective CD8+ T cell epitopes in the HIV proteome
Mutationally constrained epitopes of variable pathogens represent promising targets for
vaccine design but are not reliably identified by sequence conservation. In this study, we …
vaccine design but are not reliably identified by sequence conservation. In this study, we …
Silicon nanoparticles as hyperpolarized magnetic resonance imaging agents
Magnetic resonance imaging of hyperpolarized nuclei provides high image contrast with little
or no background signal. To date, in vivo applications of prehyperpolarized materials have …
or no background signal. To date, in vivo applications of prehyperpolarized materials have …
Rapid, efficient functional characterization and recovery of HIV-specific human CD8+ T cells using microengraving
…, KM Law, AO Ogunniyi, MN Anahtar… - Proceedings of the …, 2012 - National Acad Sciences
The nature of certain clinical samples (tissue biopsies, fluids) or the subjects themselves (pediatric
subjects, neonates) often constrain the number of cells available to evaluate the …
subjects, neonates) often constrain the number of cells available to evaluate the …
Changes in concentrations of cervicovaginal immune mediators across the menstrual cycle: a systematic review and meta-analysis of individual patient data
SM Hughes, CN Levy, R Katz, EM Lokken, MN Anahtar… - BMC medicine, 2022 - Springer
Background Hormonal changes during the menstrual cycle play a key role in shaping
immunity in the cervicovaginal tract. Cervicovaginal fluid contains cytokines, chemokines, …
immunity in the cervicovaginal tract. Cervicovaginal fluid contains cytokines, chemokines, …
Intrathecal inflammatory responses in the absence of SARS-CoV-2 nucleic acid in the CSF of COVID-19 hospitalized patients
…, G Adams, M Rudy, IH Solomon, MN Anahtar… - Journal of the …, 2021 - Elsevier
Objective Little is known about CSF profiles in patients with acute COVID-19 infection and
neurological symptoms. Here, CSF was tested for SARS-CoV-2 RNA and inflammatory …
neurological symptoms. Here, CSF was tested for SARS-CoV-2 RNA and inflammatory …
Clinical assessment and validation of a rapid and sensitive SARS-CoV-2 test using reverse transcription loop-mediated isothermal amplification without the need for …
MN Anahtar, GEG McGrath, BA Rabe… - Open Forum …, 2021 - academic.oup.com
Background Amid the enduring pandemic, there is an urgent need for expanded access to
rapid, sensitive, and inexpensive coronavirus disease 2019 (COVID-19) testing worldwide …
rapid, sensitive, and inexpensive coronavirus disease 2019 (COVID-19) testing worldwide …
