Background Angiogenesis plays a role in the biology of ovarian cancer. We examined the
effect of bevacizumab, the vascular endothelial growth factor inhibitor, on survival in women …

Intra-abdominal tumors, such as ovarian cancer 1 , 2 , have a clear predilection for metastasis
to the omentum, an organ primarily composed of adipocytes. Currently, it is unclear why …

Phosphatidylinositol 3-kinase (PI3K)/AKT pathway aberrations are common in cancer. By
applying mass spectroscopy–based sequencing and reverse-phase protein arrays to 547 …

Metaplastic breast cancers (MBC) are aggressive, chemoresistant tumors characterized by
lineage plasticity. To advance understanding of their pathogenesis and relatedness to other …

Background The ICON7 trial previously reported improved progression-free survival in women
with ovarian cancer with the addition of bevacizumab to standard chemotherapy, with the …

ContextSore throat is a common complaint, and identifying patients with group A β-hemolytic
streptococcal pharyngitis (strep throat) is an important task for clinicians. Previous reviews …

This paper establishes empirically the existence of specialization in private‐market
corporate lending, adding a new dimension to the public versus private debt distinctions now …

Internal credit risk rating systems are becoming an increasingly important element of large
commercial banks’ measurement and management of the credit risk of both individual …

Purpose The prevalence of BRCA½ mutations in germline DNA from unselected ovarian
cancer patients is 11% to 15.3%. It is important to determine the frequency of somatic BRCA½ …

Climate change is producing profound changes globally. Yet we still know little about how it
affects real people in real places on a daily basis because most of our knowledge comes …