Rationale: The vicious cycle hypothesis of bronchiectasis argues that bacterial colonization
leads to airway inflammation and progressive lung damage. The logical extension of this …

Background Cough is one of the most common presenting symptoms to general practitioners.
The objective of this article is to collate the pediatric components of the CHEST chronic …

Background Multi-disciplinary rehabilitation is recommended for individuals with post-acute
sequelae of COVID-19 infection (ie, symptoms 3–4 weeks after acute infection). There are …

Background Mannose-binding lectin (MBL) is a key component of innate immunity. MBL
deficiency is common (10–30% of the general population depending on the definition used) and …

The COVID-19 pandemic has resulted in significant acute morbidity and mortality worldwide.
There is now a growing recognition of the longer-term sequelae of this infection, termed “…

The purpose of this state-of-the-art review is to update the American College of Chest
Physicians 2006 guideline on global physiology and pathophysiology of cough. A review of the …

Background: Up to 53% of individuals who had mild COVID-19 experience symptoms for >3-month
following infection (Long-CoV). Dyspnea is reported in 60% of Long-CoV cases and …

Background Whether gastroesophageal reflux (GER) or GER disease (GERD) causes
chronic cough in children is controversial. Using the Population, Intervention, Comparison, …

The evidence used in this review was obtained from a search of PubMed for articles
published in English between January 2005 and March 2016. The medical subject headings “…

Background Asthma and non-asthmatic eosinophilic bronchitis (NAEB) are among the
commonest causes of chronic cough in adults. We sought to determine the role of non-invasive …