[HTML][HTML] Photodynamic therapy in neurosurgery: a review

H Kostron, A Obwegeser, R Jakober - Journal of Photochemistry and …, 1996 - Elsevier
Photodynamic therapy (PDT) has been investigated extensively, both experimentally and
clinically, as an adjunctive treatment in the neuro-oncological field. It is based on the more …

Photodynamic diagnosis and therapy and the brain

H Kostron - Photodynamic Therapy: Methods and Protocols, 2010 - Springer
… The activation sources ranged from various lamps, by argon-dye laser (Aurora M), KTP dye
laser and gold vapour lasers, whereas now diode lasers and LEDs are the current standard. …

Uptake and kinetics of 14C-labelled meta-tetrahydroxyphenylchlorin and 5-aminolaevulinic acid in the C6 rat glioma model

A Obwegeser, R Jakober, H Kostron - British journal of cancer, 1998 - nature.com
… After 7 days, the concentration of m-THPC decreased to 76 … of m-THPC and 5-ALA in brain
tumours. Becauseof the different pharmacokinetic and toxicological profile, we recommend m-…

mTHPC‐mediated Photodynamic Diagnosis of Malignant Brain Tumors¶

…, M Ritsch‐Marte, H Kostron - Photochemistry and …, 2001 - Wiley Online Library
Radical tumor resection is the basis for the prolonged survival of patients suffering from
malignant brain tumors such as glioblastoma multiforme. We have carried out a phase‐II study …

A characterization of the nucleotide uptake by chromaffin granules of bovine adrenal medulla

W Aberer, H Kostron, E Huber, H Winkler - Biochemical Journal, 1978 - portlandpress.com
… Chromaffin granules were incubated for 5 min at 37C in Tris/HCl (0.01 M)-buffered 0.3 M-sucrose
of various pH values. The results for the uptake of [3H]ATP (M) are mean values of …

[HTML][HTML] NovoTTF-100A versus physician's choice chemotherapy in recurrent glioblastoma: a randomised phase III trial of a novel treatment modality

…, M Westphal, M Smrcka, L Chin, H Kostron… - European journal of …, 2012 - Elsevier
PURPOSE: NovoTTF-100A is a portable device delivering low-intensity, intermediate
frequency electric fields via non-invasive, transducer arrays. Tumour Treatment Fields (TTF), a …

Clinical and experimental results of photodynamic therapy in neurosurgery

H Kostron, BW Hochleitner… - 5th International …, 1995 - spiedigitallibrary.org
Since 1984, 58 patients bearing malignant brain tumors were treated 70 times with photodynamic
treatment (PDT). The patient population consisted of 11 primary glioblastoma WHO …

Glial cell line-derived neurotrophic factor (GDNF) and its receptor (GFR-α1) are strongly expressed in human gliomas

B Wiesenhofer, G Stockhammer, H Kostron… - Acta …, 2000 - Springer
… The enzyme reaction was stopped by adding 100 µl 1 M phosphoric acid per well, and the
absorbance was measured at 450 nm. Samples were calculated from the standard curve in …

mTHPC-mediated photodynamic detection for fluorescence-guided resection of brain tumors

H Kostron, A Zimmermann… - Surgical-Assist …, 1998 - spiedigitallibrary.org
… l5mgfkg bw m-THPC. On day 4 intraoperative PDD and fluorescence guided tumor resection
(FGR… The second generation PS mTHPC proved to be superior regarding phototoxicity and …

Vascular endothelial growth factor (VEGF) is elevated in brain tumor cysts and correlates with tumor progression

G Stockhammer, A Obwegeser, H Kostron… - Acta …, 2000 - Springer
Vascular endothelial growth factor (VEGF), a key regulatory protein in neoangiogenesis, is
strongly expressed in a variety of primary brain tumors, particularly malignant gliomas. In …