We herein present an overview of the upcoming 5 th edition of the World Health Organization
Classification of Haematolymphoid Tumours focussing on lymphoid neoplasms. Myeloid …

The human genome is thought to harbor 50,000 to 100,000 genes, of which about half have
been sampled to date in the form of expressed sequence tags. An international consortium …

The fly Drosophila melanogaster is one of the most intensively studied organisms in biology
and serves as a model system for the investigation of many developmental and cellular …

INTRODUCTION The cerebral cortex underlies our complex cognitive capabilities.
Variations in human cortical surface area and thickness are associated with neurological, …

To correlate the variable clinical features of oestrogen-receptor-positive breast cancer with
somatic alterations, we studied pretreatment tumour biopsies accrued from patients in two …

Background In a phase 1–2 trial of albumin-bound paclitaxel (nab-paclitaxel) plus gemcitabine,
substantial clinical activity was noted in patients with advanced pancreatic cancer. We …

OBJECTIVE To evaluate the prevalence and time trends for diagnosed and undiagnosed
diabetes, impaired fasting glucose, and impaired glucose tolerance in US adults by age, sex, …

Genomic sequencing has made it clear that a large fraction of the genes specifying the core
biological functions are shared by all eukaryotes. Knowledge of the biological role of such …

beta-Amyloid is a 39- to 43-amino-acid neurotoxic peptide that aggregates to form the core of
Alzheimer disease-associated senile (amyloid) plaques. No satisfactory hypothesis has yet …

… Twenty microlitres of 1 M HClO 4 was added and this solution was extracted with 11.75/13.25
(v/… We thank M. Liu for technical assistance. REG is supported by funding from the National …