User profiles for M. R. Sears
Malcolm SearsProfessor of Medicine, McMaster University Verified email at mcmaster.ca Cited by 51827 |
[HTML][HTML] Asthma: epidemiology, etiology and risk factors
Methods This paper arose from an extensive literature review undertaken in developing the
Canadian Healthy Infant Longitudinal Development (CHILD) study, a multicentre national …
Canadian Healthy Infant Longitudinal Development (CHILD) study, a multicentre national …
The respiratory effects of cannabis dependence in young adults
Aim. To evaluate the relationship between cannabis dependence and respiratory symptoms
and lung function in young adults, while controlling for the effects of tobacco smoking. …
and lung function in young adults, while controlling for the effects of tobacco smoking. …
Adverse effects of β-agonists
MR Sears - Journal of Allergy and Clinical Immunology, 2002 - Elsevier
… Dr Sears: I believe that what happened was that when fenoterol was launched, we used
it particularly in patients with troublesome asthma, quite unaware that we were unknowingly …
it particularly in patients with troublesome asthma, quite unaware that we were unknowingly …
A gradient of childhood self-control predicts health, wealth, and public safety
Policy-makers are considering large-scale programs aimed at self-control to improve citizens’
health and wealth and reduce crime. Experimental and economic studies suggest such …
health and wealth and reduce crime. Experimental and economic studies suggest such …
An official American Thoracic Society/European Respiratory Society statement: asthma control and exacerbations: standardizing endpoints for clinical asthma trials …
Background: The assessment of asthma control is pivotal to the evaluation of treatment
response in individuals and in clinical trials. Previously, asthma control, severity, and …
response in individuals and in clinical trials. Previously, asthma control, severity, and …
[HTML][HTML] A longitudinal, population-based, cohort study of childhood asthma followed to adulthood
Background The outcome of childhood asthma in adults has been described in high-risk
cohorts, but few population-based studies have reported the risk factors for persistence and …
cohorts, but few population-based studies have reported the risk factors for persistence and …
Early infancy microbial and metabolic alterations affect risk of childhood asthma
…, A Becker, KM McNagny, MR Sears… - Science translational …, 2015 - science.org
Asthma is the most prevalent pediatric chronic disease and affects more than 300 million
people worldwide. Recent evidence in mice has identified a “critical window” early in life where …
people worldwide. Recent evidence in mice has identified a “critical window” early in life where …
Association between children's experience of socioeconomic disadvantage and adult health: a life-course study
Background Research into social inequalities in health has tended to focus on low
socioeconomic status in adulthood. We aimed to test the hypothesis that children's experience of …
socioeconomic status in adulthood. We aimed to test the hypothesis that children's experience of …
Regular inhaled beta-agonist treatment in bronchial asthma
MR Sears, DR Taylor, CG Print, DC Lake, Q Li… - The Lancet, 1990 - Elsevier
89 subjects with stable asthma took part in a double-blind, placebo-controlled, randomised,
crossover study of the effects of regular versus on-demand inhaled bronchodilator therapy. …
crossover study of the effects of regular versus on-demand inhaled bronchodilator therapy. …
[HTML][HTML] Relation between airway responsiveness and serum IgE in children with asthma and in apparently normal children
MR Sears, B Burrows, EM Flannery… - … England Journal of …, 1991 - Mass Medical Soc
Background. Although asthma diagnosed by a physician is known to be related to serum
IgE levels, it is not known whether there is a relation between the level of IgE and airway …
IgE levels, it is not known whether there is a relation between the level of IgE and airway …