Intracellular lipid-binding proteins and their genes
DA Bernlohr, MA Simpson, AV Hertzel… - Annual review of …, 1997 - annualreviews.org
… The mutant protein was no longer able to bind the fluorescent fatty acid analog cis-parinaric
acid, nor would it adhere to a long-chain fatty acid affinity column (MA Simpson, DA Bernlohr…
acid, nor would it adhere to a long-chain fatty acid affinity column (MA Simpson, DA Bernlohr…
[HTML][HTML] Endovascular therapy for ischemic stroke with perfusion-imaging selection
Background Trials of endovascular therapy for ischemic stroke have produced variable
results. We conducted this study to test whether more advanced imaging selection, recently …
results. We conducted this study to test whether more advanced imaging selection, recently …
[HTML][HTML] γ-Secretase mutations in hidradenitis suppurativa: new insights into disease pathogenesis
AE Pink, MA Simpson, N Desai, RC Trembath… - Journal of Investigative …, 2013 - Elsevier
Hidradenitis suppurativa (HS) is a debilitating chronic inflammatory skin condition of unclear
etiology. It may segregate as an autosomal dominant trait, and heterozygous mutations in …
etiology. It may segregate as an autosomal dominant trait, and heterozygous mutations in …
Emerging roles for hyaluronidase in cancer metastasis and therapy
CO McAtee, JJ Barycki, MA Simpson - Advances in cancer research, 2014 - Elsevier
… The quantity of HA production was attributable to elevated expression of a single isozyme
orthologue of the human HA synthase HAS2, which also produces HA of high-molecular mass …
orthologue of the human HA synthase HAS2, which also produces HA of high-molecular mass …
Precise genome modification in the crop species Zea mays using zinc-finger nucleases
…, GE Katibah, G Zhifang, D McCaskill, MA Simpson… - Nature, 2009 - nature.com
… From left to right, the labels at the top of the panel indicate molecular mass markers, wild-type
HiII and targeted integration (TI) event numbers. At the bottom of the panel, TI/- indicates …
HiII and targeted integration (TI) event numbers. At the bottom of the panel, TI/- indicates …
[HTML][HTML] Assessment of minimal residual disease in standard-risk AML
A Ivey, RK Hills, MA Simpson… - … England Journal of …, 2016 - Mass Medical Soc
Background Despite the molecular heterogeneity of standard-risk acute myeloid leukemia (AML),
treatment decisions are based on a limited number of molecular genetic markers and …
treatment decisions are based on a limited number of molecular genetic markers and …
Infantile-onset symptomatic epilepsy syndrome caused by a homozygous loss-of-function mutation of GM3 synthase
We identified an autosomal recessive infantile-onset symptomatic epilepsy syndrome associated
with developmental stagnation and blindness. Assuming a founder effect in a large Old …
with developmental stagnation and blindness. Assuming a founder effect in a large Old …
[PDF][PDF] Mutations in IL36RN/IL1F5 are associated with the severe episodic inflammatory skin disease known as generalized pustular psoriasis
A Onoufriadis, MA Simpson, AE Pink… - The American Journal of …, 2011 - cell.com
Generalized pustular psoriasis (GPP) is a rare and yet potentially lethal clinical variant of
psoriasis, characterized by the formation of sterile cutaneous pustules, neutrophilia, fever and …
psoriasis, characterized by the formation of sterile cutaneous pustules, neutrophilia, fever and …
Mutations in GATA2 cause primary lymphedema associated with a predisposition to acute myeloid leukemia (Emberger syndrome)
We report an allelic series of eight mutations in GATA2 underlying Emberger syndrome, an
autosomal dominant primary lymphedema associated with a predisposition to acute myeloid …
autosomal dominant primary lymphedema associated with a predisposition to acute myeloid …
Diagnostic strategies in CADASIL
HS Markus, RJ Martin, MA Simpson, YB Dong, N Ali… - Neurology, 2002 - AAN Enterprises
Background: Cerebral autosomal dominant arteriopathy with subcortical infarcts and
leukoencephalopathy (CADASIL) is an inherited autosomal dominant condition characterized by …
leukoencephalopathy (CADASIL) is an inherited autosomal dominant condition characterized by …