The osteocyte, a terminally differentiated cell comprising 90%–95% of all bone cells 1 , 2 ,
may have multiple functions, including acting as a mechanosensor in bone (re)modeling 3 . …

Since the publication of the Duchenne muscular dystrophy (DMD) care considerations in
2010, multidisciplinary care of this severe, progressive neuromuscular disease has evolved. In …

A coordinated, multidisciplinary approach to care is essential for optimum management of
the primary manifestations and secondary complications of Duchenne muscular dystrophy (…

Background: Based on regional and anecdotal reports, there is concern that vitamin D–deficiency
rickets is persistent in Canada despite guidelines for its prevention. We sought to …

The International Society for Clinical Densitometry Official Positions on reporting of
densitometry results in children rep resent an effort to consolidate opinions to assist healthcare …

Osteogenesis imperfecta (OI) is a heritable disease of bone in which the hallmark is bone
fragility. Usually, the disorder is divided into four groups on clinical grounds. We previously …

Improvements in the function, quality of life, and longevity of patients with Duchenne
muscular dystrophy (DMD) have been achieved through a multidisciplinary approach to …

Background X-linked hypophosphataemia in children is characterised by elevated serum
concentrations of fibroblast growth factor 23 (FGF23), hypophosphataemia, rickets, lower …

Context: As awareness of osteoporosis in childhood has increased, so have pressures to
consider use of the pharmacological agents used to treat osteoporosis in adults. This review …

Vertebral compression is a serious complication of childhood acute lymphoblastic leukemia
(ALL). The prevalence and pattern of vertebral fractures, as well as their relationship to BMD …